Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.46 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | APP | P05067 | 3/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | IAPP | P10997 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.39 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4566308 | 1.00 | BAZ2B (0.46) | BAZ2BBAZ2AGAAHTTALDH1A1 | |
| SCHEMBL19500071 | 0.87 | TTR (0.47) | BAZ2BBAZ2AGAAHTTALDH1A1 | |
| SCHEMBL23952005 | 0.83 | BAZ2B (0.49) | BAZ2BBAZ2AGAAALDH1A1LMNA | |
| SCHEMBL13658710 | 0.83 | TDP1 (0.50) | GAAHTTALDH1A1APPGLA | |
| SCHEMBL12287050 | 0.83 | GLA (0.46) | GAAHTTALDH1A1APPGLA | |
| SCHEMBL9197132 | 0.82 | BAZ2B (0.47) | BAZ2BBAZ2AGAAALDH1A1LMNA | |
| SCHEMBL1081773 | 0.81 | ALDH1A1 (0.42) | BAZ2BBAZ2AGAAHTTALDH1A1 | |
| SCHEMBL1006833 | 0.81 | ALDH1A1 (0.42) | BAZ2BBAZ2AGAAHTTALDH1A1 | |
| SCHEMBL1006832 | 0.81 | ALDH1A1 (0.42) | BAZ2BBAZ2AGAAHTTALDH1A1 | |
| SCHEMBL1003723 | 0.80 | BAZ2B (0.51) | BAZ2BBAZ2AGAAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009125191-A1 | BENZENE DERIVATIVES | UNIVERSITY COLLEGE CARDIFF CONSULTANTS LIMITED (GB) | 2009-10-15 | — | — | WO | disclosed |