Styrene

Styrene

SCHEMBL4566718

C=Cc1ccccc1.C=Cc1ccccc1C(N)=O

nearest known ligand 0.50

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.50
TSHR P16473 3/20 0.50
KDM4E B2RXH2 4/20 0.47
HPGD P15428 4/20 0.47
MAPT P10636 4/20 0.47
LMNA P02545 2/20 0.47
PARP1 P09874 3/20 0.44
SIRT2 Q8IXJ6 1/20 0.43
BCAT2 O15382 1/20 0.43
HSD17B10 Q99714 2/20 0.42
METAP2 P50579 1/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
SIRT1 Q96EB6 2/20 0.40
HTT P42858 1/20 0.40
CTNNB1 P35222 1/20 0.40
NPC1 O15118 2/20 0.39
RAB9A P51151 1/20 0.39
AKR1C3 P42330 2/20 0.38
AKR1C2 P52895 1/20 0.38
AKR1C1 Q04828 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL28389934 0.93 ALDH1A1 (0.50) ALDH1A1TSHRKDM4EHPGDMAPT
SCHEMBL1004375 0.91 ALDH1A1 (0.50) ALDH1A1TSHRKDM4EHPGDMAPT
SCHEMBL30053495 0.89 ALDH1A1 (0.48) ALDH1A1TSHRKDM4EHPGDMAPT
Styrene SCHEMBL2118111 0.85 ALDH1A1 (0.54) ALDH1A1TSHRKDM4EHPGDMAPT
Acrylamide SCHEMBL10534971 0.85 ALDH1A1 (0.45) ALDH1A1TSHRKDM4EHPGDMAPT
Styrene SCHEMBL28935148 0.82 ALDH1A1 (0.50) ALDH1A1TSHRKDM4EHPGDMAPT
Styrene SCHEMBL9741465 0.81 ALDH1A1 (0.54) ALDH1A1TSHRKDM4EMAPTLMNA
Styrene SCHEMBL28828180 0.81 ALDH1A1 (0.54) ALDH1A1TSHRKDM4EHPGDMAPT
Styrene SCHEMBL2033347 0.80 ALDH1A1 (0.70) ALDH1A1TSHRKDM4EHPGDMAPT
Styrene SCHEMBL5164588 0.80 ALDH1A1 (0.70) ALDH1A1TSHRKDM4EHPGDMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7531334-B2 Polymeric microcarriers for cell culture functions XEROX CORPORATION (US) 2009-05-12 US disclosed
US-20070243607-A1 POLYMERIC MICROCARRIERS FOR CELL CULTURE FUNCTIONS XEROX CORPORATION (US) 2007-10-18 US disclosed
US-7276254-B2 Emulsion/aggregation polymeric microspheres for biomedical applications and methods of making same XEROX CORPORATION (US) 2007-10-02 US disclosed
US-20030211035-A1 Emulsion/aggregation polymeric microspheres for biomedical applications and methods of making same XEROX CORPORATION 2003-11-13 US disclosed