Styrene

Styrene

SCHEMBL2118111

C=Cc1ccccc1.C=Cc1ccccc1C(=O)O

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.54
TSHR P16473 1/20 0.54
ALOX15 P16050 1/20 0.48
LMNA P02545 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP2C9 P11712 1/20 0.42
KDM4E B2RXH2 3/20 0.42
HPGD P15428 2/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
HMGB1 P09429 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA7 P43166 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
CA9 Q16790 1/20 0.42
NAPRT Q6XQN6 1/20 0.42
CA14 Q9ULX7 1/20 0.42
GRIK1 P39086 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL28935148 0.96 ALDH1A1 (0.50) ALDH1A1TSHRALOX15LMNACYP1A2
Benzene SCHEMBL28254104 0.92 ALDH1A1 (0.56) ALDH1A1ALOX15LMNACYP1A2CYP2C9
SCHEMBL31100 0.92 ALDH1A1 (0.56) ALDH1A1ALOX15LMNACYP1A2CYP2C9
SCHEMBL30259301 0.92 ALDH1A1 (0.56) ALDH1A1ALOX15LMNACYP1A2CYP2C9
Styrene SCHEMBL3545858 0.90 ALDH1A1 (0.44) ALDH1A1TSHRALOX15LMNACYP1A2
SCHEMBL2856375 0.90 ALDH1A1 (0.54) ALDH1A1ALOX15LMNACYP1A2CYP2C9
SCHEMBL347539 0.90 ALDH1A1 (0.54) ALDH1A1ALOX15LMNACYP1A2CYP2C9
SCHEMBL2867924 0.90 ALDH1A1 (0.54) ALDH1A1ALOX15LMNACYP1A2CYP2C9
Ammonia Solution, Strong SCHEMBL6551345 0.90 ALDH1A1 (0.54) ALDH1A1ALOX15LMNACYP1A2CYP2C9
Fluoride SCHEMBL31173776 0.90 ALDH1A1 (0.54) ALDH1A1ALOX15LMNACYP1A2CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-56154733-A None JP disclosed
US-8444961-B2 RNA virus infection inhibitor, method for inhibition of infection by RNA virus, RNA virus infection-inhibiting product, and use as RNA virus infection inhibitor SEKISUI CHEMICAL CO., LTD. (JP) 2013-05-21 US disclosed
EP-2444095-A1 RNA VIRUS INFECTION INHIBITOR, METHOD FOR INHIBITION OF INFECTION BY RNA VIRUS, PRODUCTS FOR INHIBITION OF INFECTION BY RNA VIRUS, AND USE AS RNA VIRUS INFECTION INHIBITOR Sekisui Chemical Co., Ltd. (JP) 2012-04-25 EP disclosed
US-20120093763-A1 RNA VIRUS INFECTION INHIBITOR, METHOD FOR INHIBITION OF INFECTION BY RNA VIRUS, RNA VIRUS INFECTION-INHIBITING PRODUCT, AND USE AS RNA VIRUS INFECTION INHIBITOR SEKISUI CHEMICAL CO., LTD. (JP) 2012-04-19 US disclosed
US-20090036608-A1 CHLOROPRENE-BASED BLOCK COPOLYMER, SOAPLESS POLYCHLOROPRENE-BASED LATEX, AND PROCESSES FOR PRODUCING THE SAME TOSOH CORPORATION (JP) 2009-02-05 US disclosed
JP-2002229151-A HEAT DEVELOPABLE PHOTOSENSITIVE MATERIAL FUJI PHOTO FILM CO LTD 2002-08-14 JP disclosed
JP-S56154733-A IMAGE FORMING MATERIAL AND FORMATION OF IMAGE USING IT TOPPAN PRINTING CO LTD 1981-11-30 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120093763-A1 RNA VIRUS INFECTION INHIBITOR, METHOD FOR INHIBITION OF INFECTION BY RNA VIRUS, RNA VIRUS INFECTION-INHIBITING PRODUCT, AND USE AS RNA VIRUS INFECTION INHIBITOR NSUN3, RNASEH1, RNASEL ALDH1A1 2981/4885TSHR 4066/4885ALOX15 4103/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.