Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 9/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | CNR1 | P21554 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11335722 | 0.88 | CNR2 (0.69) | CNR2ALDH1A1HPGDKMT2ACNR1 | |
| SCHEMBL7855746 | 0.88 | CNR2 (0.69) | CNR2ALDH1A1HPGDKMT2ACNR1 | |
| SCHEMBL7378852 | 0.85 | CNR2 (0.65) | CNR2ALDH1A1HPGDKMT2ACNR1 | |
| SCHEMBL7378854 | 0.85 | CNR2 (0.65) | CNR2ALDH1A1HPGDKMT2ACNR1 | |
| SCHEMBL1363688 | 0.84 | CNR2 (0.46) | CNR2ALDH1A1HPGDKMT2ACNR1 | |
| SCHEMBL13447506 | 0.84 | CTSC (0.46) | CNR2ALDH1A1HPGDKMT2ACNR1 | |
| SCHEMBL1363689 | 0.84 | CNR2 (0.46) | CNR2ALDH1A1HPGDKMT2ACNR1 | |
| SCHEMBL18196590 | 0.83 | LMNA (0.50) | CNR2ALDH1A1HPGDKMT2ACNR1 | |
| SCHEMBL12182395 | 0.83 | LMNA (0.50) | CNR2ALDH1A1HPGDKMT2ACNR1 | |
| SCHEMBL8303023 | 0.82 | CNR2 (0.49) | CNR2ALDH1A1HPGDKMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096565-B2 | Inhibitors of histone deacetylase | METHYLGENE INC. (CA) | 2015-08-04 | — | — | US | disclosed |
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | METHYLGENE INC. (CA) | 2009-07-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090181943-A1 | Inhibitors of Histone Deacetylase | HDAC1, HDAC11, HDAC3 | CNR2 3937/4885ALDH1A1 532/4885HPGD 215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.