Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 11/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8302507 | 0.87 | CNR2 (0.44) | CNR2EPHX1ALDH1A1HPGDKMT2A | |
| SCHEMBL4566800 | 0.82 | CNR2 (0.67) | CNR2ALDH1A1HPGDKMT2ACNR1 | |
| SCHEMBL8305615 | 0.81 | CNR2 (0.46) | CNR2HPGDKMT2AMAPT | |
| SCHEMBL8306394 | 0.75 | TACR3 (0.40) | EPHX1ALDH1A1HPGDCNR1MAPT | |
| SCHEMBL4732145 | 0.72 | LMNA (0.49) | CNR2EPHX1CNR1 | |
| SCHEMBL22502277 | 0.72 | LMNA (0.49) | CNR2EPHX1CNR1 | |
| SCHEMBL10332571 | 0.72 | LMNA (0.53) | CNR2EPHX1ALDH1A1CNR1 | |
| SCHEMBL18925994 | 0.71 | ATM (0.65) | ALDH1A1 | |
| SCHEMBL17776392 | 0.71 | ATM (0.65) | ALDH1A1 | |
| SCHEMBL13538435 | 0.71 | CTSC (0.57) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004085661-A2 | PROCESS TO CHIRAL BETA-AMINO ACID DERIVATIVES | MERCK & CO., INC (US) | 2004-10-07 | — | — | WO | disclosed |