Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 7/20 | 0.48 |
| ▸ | F10 | P00742 | 13/20 | 0.38 |
| ▸ | F2 | P00734 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3247455 | 0.68 | HRH3 (0.57) | HRH3 | |
| SCHEMBL4366003 | 0.68 | HRH3 (0.53) | HRH3F10 | |
| SCHEMBL5023553 | 0.66 | HRH3 (0.85) | HRH3 | |
| SCHEMBL4364693 | 0.66 | HRH3 (0.49) | HRH3F10 | |
| SCHEMBL4363405 | 0.66 | HRH3 (0.46) | HRH3 | |
| SCHEMBL1552105 | 0.66 | HRH3 (0.76) | HRH3 | |
| SCHEMBL1553226 | 0.65 | HRH3 (0.71) | HRH3 | |
| SCHEMBL5017103 | 0.65 | HRH3 (1.00) | HRH3 | |
| SCHEMBL1375636 | 0.65 | HRH3 (1.00) | HRH3 | |
| SCHEMBL3538141 | 0.64 | HRH3 (0.63) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2118089-A1 | INDOL-2-YL-PIPERAZIN-1-YL-METHANONE DERIVATIVES | F. Hoffmann-Roche AG (CH) | 2009-11-18 | — | — | EP | disclosed |
| WO-2008095821-A1 | INDOL-2-YL-PIPERAZIN-1-YL-METHANONE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2008-08-14 | — | — | WO | disclosed |