Styrene

Styrene

SCHEMBL4566873

C=CC(=O)C=CC#N.C=CCOC(=O)C=C.C=Cc1ccccc1

nearest known ligand 0.39

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.39
THRB P10828 1/20 0.39
MAPT P10636 4/20 0.38
KDM4E B2RXH2 3/20 0.38
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
LMNA P02545 2/20 0.38
MAPK1 P28482 2/20 0.38
GAA P10253 1/20 0.38
APP P05067 1/20 0.38
CASP1 P29466 2/20 0.36
ALDH1A1 P00352 5/20 0.35
TSHR P16473 4/20 0.35
HSD17B10 Q99714 3/20 0.35
PKM P14618 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
NPSR1 Q6W5P4 2/20 0.33
ALOX12 P18054 1/20 0.33
PTP4A3 O75365 1/20 0.33
PTP4A1 Q93096 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL5613413 0.88 CYP3A4 (0.44) CYP3A4THRBMAPTKDM4EMEN1
Styrene SCHEMBL5072723 0.87 ALDH1A1 (0.47) MAPTMEN1KMT2ALMNAALDH1A1
Styrene SCHEMBL1803177 0.86 CYP3A4 (0.42) CYP3A4THRBMAPTKDM4EMEN1
Styrene SCHEMBL167641 0.85 CYP3A4 (0.51) CYP3A4THRBMAPTKDM4EMEN1
Styrene SCHEMBL5069331 0.84 ALDH1A1 (0.44) THRBMAPTMEN1KMT2ALMNA
Styrene SCHEMBL27446647 0.84 CYP3A4 (0.40) CYP3A4THRBMAPTKDM4EMEN1
Styrene SCHEMBL3117319 0.82 CYP3A4 (0.49) CYP3A4THRBMAPTKDM4EMEN1
Styrene SCHEMBL5460311 0.81 MAPT (0.42) CYP3A4THRBMAPTKDM4EMEN1
Styrene SCHEMBL7194534 0.81 CYP3A4 (0.38) CYP3A4THRBMAPTKDM4EMEN1
Styrene SCHEMBL1255712 0.81 CYP3A4 (0.40) CYP3A4MAPTKDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090047595-A1 Nano-Sized Composites Containing Polymer Modified Clays and Method for Making Toner Particles Using Same XEROX CORPORATION (US) 2009-02-19 US disclosed