Styrene

Styrene

SCHEMBL5069331

C=CC(=O)C=CC#N.C=CC=C.C=Cc1ccccc1

nearest known ligand 0.44

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.44
TSHR P16473 1/20 0.44
LMNA P02545 4/20 0.38
MAPT P10636 3/20 0.38
PLIN1 O60240 2/20 0.38
RECQL P46063 2/20 0.38
PLIN5 Q00G26 2/20 0.38
ABHD5 Q8WTS1 2/20 0.38
CYP1A2 P05177 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
F3 P13726 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
GSR P00390 1/20 0.37
MCL1 Q07820 2/20 0.35
HDAC3 O15379 3/20 0.34
HDAC4 P56524 3/20 0.34
HDAC1 Q13547 3/20 0.34
HDAC2 Q92769 3/20 0.34
HDAC8 Q9BY41 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL5072723 0.97 ALDH1A1 (0.47) ALDH1A1TSHRLMNAMAPTPLIN1
Styrene SCHEMBL4566873 0.84 CYP3A4 (0.39) ALDH1A1TSHRLMNAMAPTSMN1; SMN2
Styrene SCHEMBL10751334 0.82 GSR (0.50) ALDH1A1TSHRLMNAMAPTPLIN1
Styrene SCHEMBL341005 0.80 ALDH1A1 (0.50) ALDH1A1TSHRLMNAMAPTPLIN1
Styrene SCHEMBL157052 0.80 ALDH1A1 (0.54) ALDH1A1TSHRLMNAMAPTPLIN1
Styrene SCHEMBL6429853 0.79 ALDH1A1 (0.45) ALDH1A1TSHRMEN1KMT2A
Styrene SCHEMBL183213 0.78 ALDH1A1 (0.52) ALDH1A1TSHRLMNAMAPTPLIN1
Styrene SCHEMBL9124799 0.78 ALDH1A1 (0.44) ALDH1A1TSHRLMNAMAPTCYP1A2
Styrene SCHEMBL9577015 0.78 ALDH1A1 (0.56) ALDH1A1TSHRMCL1HDAC8TDP1
Styrene SCHEMBL9576998 0.77 ALDH1A1 (0.67) ALDH1A1TSHRLMNAMCL1HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0933183-B1 SHEET FOR MOLDED-IN FOIL DECORATION AND METHOD OF PRODUCING MOLDED RESIN HAVING MOLDED-IN FOIL DECORATION BY USING THE SHEET NISSHA PRINTING (JP) 2008-11-19 EP disclosed
US-6866938-B2 Foil-detecting sheet and method of producing a foil-decorated resin article using the same NISSHA PRINTING CO., LTD. (JP) 2005-03-15 US disclosed
US-20020058144-A1 Foil-decorating sheet and method of producing a foil-decorated resin article using the same NISSHA PRINTING CO., LTD. (JP) 2002-05-16 US disclosed
US-6326086-B1 TRANSPARENT ACRYLIC FILM LAMINATED ON POLYPROPYLENE RESIN LOADED WITH A STYRENE ELASTOMER USED FOR THREE-DIMENSIONAL SHAPE AUTOMOTIVE TRIMS NISSHA PRINTING CO., LTD. (JP) 2001-12-04 US disclosed
EP-0933183-A1 SHEET FOR MOLDED-IN FOIL DECORATION AND METHOD OF PRODUCING MOLDED RESIN HAVING MOLDED-IN FOIL DECORATION BY USING THE SHEET NISSHA PRINTING CO., LTD. (JP) 1999-08-04 EP disclosed