SCHEMBL456705

SCHEMBL456705

CC(=O)OCC1(COC(C)=O)CC2C=CC1C2

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.37
CYP2C19 P33261 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13025197 0.82 CYP2D6 (0.36) CYP2D6CYP2C19
SCHEMBL3098088 0.81 CYP2D6 (0.34) CYP2D6CYP2C19
SCHEMBL3089606 0.80 CYP2D6 (0.33) CYP2D6CYP2C19
SCHEMBL3087969 0.79 CYP2D6 (0.35) CYP2D6CYP2C19
SCHEMBL3087502 0.79 CYP2D6 (0.33) CYP2D6CYP2C19
SCHEMBL3093537 0.78 CYP2D6 (0.31) CYP2D6CYP2C19
SCHEMBL3093365 0.78 CYP2D6 (0.32) CYP2D6CYP2C19
SCHEMBL7067453 0.77 CYP2D6 (0.39) CYP2D6CYP2C19
SCHEMBL3094272 0.76 CYP2D6 (0.33) CYP2D6CYP2C19
SCHEMBL3101087 0.76 CYP2D6 (0.31) CYP2D6CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2634197-B1 CATALYST FOR NORBORNENE MONOMER POLYMERIZATION AND METHOD FOR PRODUCING NORBORNENE POLYMER SHOWA DENKO KK (JP) 2017-05-31 EP disclosed
EP-2614091-B1 CATALYST FOR POLYMERIZING NORBORNENE MONOMERS AND A METHOD FOR PRODUCING NORBORNENE POLYMER SHOWA DENKO KK (JP) 2016-04-20 EP disclosed
CN-103080150-B Catalyst for polymerization of norbornene monomer and method for preparing norbornene polymer SHOWA DENKO KABUSHIKI KAISHA (JP) 2015-09-02 CN disclosed
CN-103189397-B Catalyst for norbornene monomer polymerization and method for producing norbornene polymer SHOWA DENKO KK 2015-06-10 CN disclosed
US-8835580-B2 Catalyst for norbornene monomer polymerization and method for producing norbornene polymer SHOWA DENKO K.K. (JP) 2014-09-16 US disclosed
US-8598288-B2 Catalyst for polymerization of norbornene monomers, method for producing norbornene polymer, method for producing norbornene copolymer, norbornene polymer and transition metal complex SHOWA DENKO K.K. (JP) 2013-12-03 US disclosed
US-20130261271-A1 CATALYST FOR NORBORNENE MONOMER POLYMERIZATION AND METHOD FOR PRODUCING NORBORNENE POLYMER SHOWA DENKO K.K. (JP) 2013-10-03 US disclosed
EP-2634197-A1 CATALYST FOR NORBORNENE MONOMER POLYMERIZATION AND METHOD FOR PRODUCING NORBORNENE POLYMER Showa Denko K.K. (JP) 2013-09-04 EP disclosed
EP-2614091-A2 CATALYST FOR POLYMERIZING NORBORNENE MONOMERS AND A METHOD FOR PRODUCING NORBORNENE POLYMER Showa Denko K.K. (JP) 2013-07-17 EP disclosed
US-20130059993-A1 CATALYST FOR POLYMERIZATION OF NORBORNENE MONOMERS, METHOD FOR PRODUCING NORBORNENE POLYMER, METHOD FOR PRODUCING NORBORNENE COPOLYMER, NORBORNENE POLYMER AND TRANSITION METAL COMPLEX SHOWA DENKO K.K. (JP) 2013-03-07 US disclosed
WO-2012033227-A2 CATALYST FOR POLYMERIZING NORBORNENE MONOMERS AND A METHOD FOR PRODUCING NORBORNENE POLYMER SHOWA DENKO K.K. (JP) 2012-03-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130059993-A1 CATALYST FOR POLYMERIZATION OF NORBORNENE MONOMERS, METHOD FOR PRODUCING NORBORNENE POLYMER, METHOD FOR PRODUCING NORBORNENE COPOLYMER, NORBORNENE POLYMER AND TRANSITION METAL COMPLEX NNMT, PPOX, DNMT1 CYP2D6 65/4885CYP2C19 687/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.