⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12335751 | 0.77 | — | — | |
| SCHEMBL25239929 | 0.77 | — | — | |
| SCHEMBL18357915 | 0.72 | — | — | |
| SCHEMBL7194664 | 0.69 | ALDH1A1 (0.50) | — | |
| SCHEMBL115473 | 0.69 | — | — | |
| SCHEMBL28259986 | 0.69 | — | — | |
| SCHEMBL25591249 | 0.69 | PDPK1 (0.31) | — | |
| SCHEMBL6001328 | 0.67 | — | — | |
| SCHEMBL8425449 | 0.67 | — | — | |
| SCHEMBL12858786 | 0.65 | HPGD (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4447944-A1 | COMPOSITIONS AND METHODS FOR TARGETED DELIVERY OF THERAPEUTIC AND/OR DIAGNOSTIC SPECIES | THE PENN STATE RESEARCH FOUNDATION (US) | 2024-10-23 | — | — | EP | disclosed |
| US-20240335540-A1 | COMPOSITIONS AND METHODS FOR TARGETED DELIVERY OF THERAPEUTIC AND/OR DIAGNOSTIC SPECIES | PENN STATE RES FOUND (US) | 2024-10-10 | — | — | US | disclosed |
| CN-118613287-A | Compositions and methods for targeted delivery of therapeutic and/or diagnostic substances | 宾夕法尼亚州立大学研究基金会 | 2024-09-06 | — | — | CN | disclosed |
| WO-2023114466-A1 | COMPOSITIONS AND METHODS FOR TARGETED DELIVERY OF THERAPEUTIC AND/OR DIAGNOSTIC SPECIES | THE PENN STATE RESEARCH FOUNDATION (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2020161052-A1 | ORGANIC SEMICONDUCTING POLYMERS | MERCK PATENT GMBH (DE) | 2020-08-13 | — | — | WO | disclosed |
| US-9039936-B2 | Thiophene derivative, method for producing same, and polymer of thiophene derivative | TOKYO INSTITUTE OF TECHNOLOGY (JP) | 2015-05-26 | — | — | US | disclosed |
| US-20120119157-A1 | THIOPHENE DERIVATIVE, METHOD FOR PRODUCING SAME, AND POLYMER OF THIOPHENE DERIVATIVE | KURARAY CO., LTD. (JP) | 2012-05-17 | — | — | US | disclosed |
| US-6074683-A | REACTING A 2-HYDROXYALKYL-SUBSTITUTED 4-HYDROXY-3(2H)-FURANONE WITH H2S AND/OR CYSTEINE | LIPTON, INC. (US) | 2000-06-13 | — | — | US | disclosed |