Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MPL | P40238 | 2/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.31 |
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24244885 | 0.81 | — | — | |
| SCHEMBL21479595 | 0.78 | MPL (0.37) | HPGDHSD17B10MPLHSD11B1MRGPRX1 | |
| SCHEMBL22733824 | 0.78 | HPGD (0.34) | HPGDHSD17B10MPL | |
| SCHEMBL21479580 | 0.78 | HPGD (0.34) | HPGDHSD17B10MPLHSD11B1MRGPRX1 | |
| SCHEMBL14817559 | 0.77 | ALDH1A1 (0.37) | HPGDHSD17B10ALDH1A1HTTNPSR1 | |
| SCHEMBL28122704 | 0.76 | HPGD (0.33) | HPGDHSD17B10MPLHSD11B1HDAC3 | |
| SCHEMBL28123347 | 0.76 | HSD17B10 (0.41) | HPGDHSD17B10MPLALDH1A1MEN1 | |
| SCHEMBL24464087 | 0.76 | HSD17B10 (0.41) | HPGDHSD17B10MPLALDH1A1MEN1 | |
| SCHEMBL8538414 | 0.75 | ALDH1A1 (0.32) | ALDH1A1DAOMEN1KMT2AHTT | |
| SCHEMBL16801386 | 0.73 | P2RX7 (0.36) | HPGDHSD17B10MPLHSD11B1MRGPRX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9868719-B2 | Compounds with pesticidal activity | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2018-01-16 | — | — | US | disclosed |
| US-20170320878-A1 | METHOD FOR PREPARATION OF FLUORO, CHLORO AND FLUOROCHLORO ALKYLATED COMPOUNDS BY HOMOGENEOUS CATALYSIS | LONZA LTD (CH) | 2017-11-09 | — | — | US | disclosed |
| US-20170320878-A1 | METHOD FOR PREPARATION OF FLUORO, CHLORO AND FLUOROCHLORO ALKYLATED COMPOUNDS BY HOMOGENEOUS CATALYSIS | LONZA LTD (CH) | 2017-11-09 | — | — | US | disclosed |
| US-9809596-B1 | Method for preparation of fluoro, chloro and fluorochloro alkylated compounds by homogeneous catalysis | LONZA LTD. (CH) | 2017-11-07 | — | — | US | disclosed |
| US-9809596-B1 | Method for preparation of fluoro, chloro and fluorochloro alkylated compounds by homogeneous catalysis | LONZA LTD. (CH) | 2017-11-07 | — | — | US | disclosed |
| US-20160198708-A1 | COMPOUNDS WITH PESTICIDAL ACTIVITY | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-07-14 | — | — | US | disclosed |
| US-20110045974-A1 | Substituted Triazinylmethyl Sulfonamides | BASF SE (DE) | 2011-02-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170320878-A1 | METHOD FOR PREPARATION OF FLUORO, CHLORO AND FLUOROCHLORO ALKYLATED COMPOUNDS BY HOMOGENEOUS CATALYSIS | AOC1, HDHD5, DDT | HPGD 3926/4885HSD17B10 4478/4885MPL 419/4885 |
| US-20110045974-A1 | Substituted Triazinylmethyl Sulfonamides | STS, TST, TPST2 | HPGD 3398/4885HSD17B10 3931/4885MPL 3436/4885 |
| US-20160198708-A1 | COMPOUNDS WITH PESTICIDAL ACTIVITY | ACHE, DDT, CAT | HPGD 656/4885HSD17B10 1581/4885MPL 3770/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.