SCHEMBL456778

SCHEMBL456778

CCCCCCCCCCC(N)[Si](OCC)(OCC)OCC

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.48
SPHK1 Q9NYA1 2/20 0.41
TP53 P04637 2/20 0.39
CYP2D6 P10635 2/20 0.38
LMNA P02545 2/20 0.38
LAP3 P28838 2/20 0.38
PLA2G1B P04054 1/20 0.38
PLA2G2A P14555 1/20 0.38
GMNN O75496 1/20 0.38
POLB P06746 1/20 0.38
THPO P40225 1/20 0.38
MTOR P42345 1/20 0.38
BLM P54132 1/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
MAPT P10636 1/20 0.38
CETP P11597 1/20 0.38
HTT P42858 1/20 0.38
UBE2N P61088 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19371537 1.00 OPRM1 (0.48) OPRM1SPHK1TP53CYP2D6LMNA
SCHEMBL2981844 1.00 OPRM1 (0.48) OPRM1SPHK1TP53CYP2D6LMNA
SCHEMBL2993823 1.00 OPRM1 (0.48) OPRM1SPHK1TP53CYP2D6LMNA
SCHEMBL957034 0.98 OPRM1 (0.50) OPRM1SPHK1TP53CYP2D6LMNA
SCHEMBL16432326 0.94 OPRM1 (0.43) OPRM1SPHK1TP53CYP2D6LMNA
SCHEMBL8586711 0.91 OPRM1 (0.41) OPRM1SPHK1TP53
Ammonia Solution, Strong SCHEMBL20421796 0.89 OPRM1 (0.39) OPRM1TP53
SCHEMBL5154702 0.86 CPB2 (0.39) OPRM1
SCHEMBL21409631 0.86 CPB2 (0.39) OPRM1
SCHEMBL21410655 0.86 OPRM1 (0.41) OPRM1SPHK1TP53CYP2D6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 218 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024088992-A1 METHOD FOR MANUFACTURING A FIRE-RESISTANT COATING MADE OF ORGANOMINERAL SILICA SAINT-GOBAIN GLASS FRANCE (FR) 2024-05-02 WO claimed
EP-4294772-A1 FIRE-RESISTANT GLAZING Saint-Gobain Glass France (FR) 2023-12-27 EP claimed
EP-4211194-A1 ANTI-MICROBIAL SURFACES AND RELATED METHODS NBD Nanotechnologies, Inc. (US) 2023-07-19 EP claimed
WO-2022055965-A9 ANTI-MICROBIAL SURFACES AND RELATED METHODS Nbd Nanotechnologies Inc. (US) 2022-05-27 WO claimed
WO-2022055965-A1 ANTI-MICROBIAL SURFACES AND RELATED METHODS Nbd Nanotechnologies Inc. (US) 2022-03-17 WO claimed
EP-3931269-A1 INVISIBLE-FINGERPRINT COATINGS AND PROCESS FOR FORMING SAME NBD Nanotechnologies, Inc. (US) 2022-01-05 EP claimed
WO-2021183115-A1 PROTECTIVE PANELS WITH ANTI-GLARE CERAMIC COATS HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2021-09-16 WO claimed
EP-3801928-A1 INVISIBLE FINGERPRINT COATINGS AND PROCESS FOR FORMING SAME Nbd Nanotechnologies, Inc. (US) 2021-04-14 EP claimed
EP-3755673-A1 ETCHED GLASS SURFACES WITH HYDROPHOBIC ALKOXYORGANOSILANES HEWLETT-PACKARD DEVELOPMENT COMPANY, L.P. (US) 2020-12-30 EP claimed
US-20200277513-A1 INVISIBLE-FINGERPRINT COATINGS AND PROCESS FOR FORMING SAME HENKEL AG & CO. KGAA (DE) 2020-09-03 US claimed
US-9382290-B2 Aptamer-modified polymeric materials for the binding of factors in a wound environment KCI LICENSING, INC. (US) 2016-07-05 US claimed
EP-3027234-A1 OSTEOINDUCTIVE MATERIALS The University of Liverpool (GB) 2016-06-08 EP claimed
US-20160149207-A1 SURFACE TREATED SILICON CONTAINING ACTIVE MATERIALS FOR ELECTROCHEMICAL CELLS NEXEON LIMITED (GB) 2016-05-26 US claimed
EP-2702068-B1 APTAMER-MODIFIED POLYMERIC MATERIALS FOR THE BINDING OF THERAPEUTIC FACTORS IN A WOUND ENVIRONMENT KCI LICENSING INC (US) 2015-07-29 EP claimed
WO-2015044188-A1 METAL EFFECT PIGMENTS MODIFIED WITH A SILANE LAYER CONTAINING AT LEAST TWO DIFFERENT BIFUNCTIONAL SILANES SCHLENK METALLIC PIGMENTS GMBH (DE) 2015-04-02 WO claimed
WO-2015015189-A1 OSTEOINDUCTIVE MATERIALS THE UNIVERSITY OF LIVERPOOL (GB) 2015-02-05 WO claimed
EP-2702068-A1 APTAMER -MODIFIED POLYMERIC MATERIALS FOR THE BINDING OF THERAPEUTIC FACTORS IN A WOUND ENVIRONMENT KCI Licensing Inc. (US) 2014-03-05 EP claimed
WO-2012149242-A1 APTAMER -MODIFIED POLYMERIC MATERIALS FOR THE BINDING OF THERAPEUTIC FACTORS IN A WOUND ENVIRONMENT KCI LICENSING, INC. (US) 2012-11-01 WO claimed
US-20120276039-A1 APTAMER-MODIFIED POLYMERIC MATERIALS FOR THE BINDING OF FACTORS IN A WOUND ENVIRONMENT KCI LICENSING, INC. (US) 2012-11-01 US claimed
WO-2010121130-A2 MOLECULAR DELIVERY WITH NANOWIRES PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2010-10-21 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120276039-A1 APTAMER-MODIFIED POLYMERIC MATERIALS FOR THE BINDING OF FACTORS IN A WOUND ENVIRONMENT SDF4, CXCL12, PCLAF OPRM1 2707/4885SPHK1 3600/4885TP53 1850/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.