Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.62 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.60 |
| ▸ | NPY5R | Q15761 | 2/20 | 0.52 |
| ▸ | KIF11 | P52732 | 2/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | PIM1 | P11309 | 1/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.44 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.44 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.42 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4884700 | 0.82 | NPC1 (0.58) | CYP19A1DGAT1KCNH2KIF11NPBWR1 | |
| SCHEMBL1605712 | 0.81 | CYP19A1 (0.68) | CYP19A1NPY5RCYP11B1CYP11B2CDK5 | |
| SCHEMBL16332961 | 0.79 | TTK (0.52) | CYP19A1DGAT1KCNH2NPY5RCDK5 | |
| SCHEMBL1605273 | 0.78 | CYP19A1 (0.68) | CYP19A1NPY5RNPC1CDK5CDK5R1 | |
| SCHEMBL2789205 | 0.78 | CYP19A1 (0.68) | CYP19A1NPY5RNPC1CDK5CDK5R1 | |
| SCHEMBL29790209 | 0.77 | CYP19A1 (1.00) | CYP19A1NPC1CYP11B1CYP11B2CDK5 | |
| SCHEMBL2789486 | 0.77 | CYP19A1 (1.00) | CYP19A1NPC1CYP11B1CYP11B2CDK5 | |
| Hydrochloric Acid SCHEMBL27830550 | 0.76 | CYP19A1 (0.97) | CYP19A1NPC1CYP11B1CYP11B2CDK5 | |
| SCHEMBL1120933 | 0.75 | CYP19A1 (0.62) | CYP19A1NPY5RNPC1CYP11B1CYP11B2 | |
| SCHEMBL17548599 | 0.75 | PTGDR2 (0.46) | DGAT1KCNH2KIF11NPBWR1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122931-A1 | INDOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2012-05-17 | — | — | US | disclosed |
| US-20120122931-A1 | INDOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122931-A1 | INDOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | PTGER1, CYSLTR1, LTB4R | CYP19A1 1262/4885DGAT1 875/4885KCNH2 895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.