SCHEMBL4568334

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4568336	0.94	GRM5 (0.38)	MAPTGRM5GABRPGABRDGABRA1
	SCHEMBL4568337	0.91	GRM5 (0.38)	GRM5TUBB4ATUBBTUBA3CTUBA1B
	SCHEMBL4568338	0.91	MAPT (0.39)	MAPTCNR1GRM5GABRPGABRD
	SCHEMBL4568335	0.90	TUBB4A (0.37)	MAPTCNR1GRM5GABRPGABRD
	SCHEMBL4568311	0.88	NPC1 (0.40)	MAPTGABRPGABRDGABRA1GABRB1
	SCHEMBL4568317	0.88	TUBB4A (0.41)	MAPTCNR1TUBB4ATUBBTUBA3C
	SCHEMBL4568346	0.87	GRM5 (0.38)	MAPTGRM5TUBB4ATUBBTUBA3C
	SCHEMBL4568313	0.86	PDE3B (0.46)	MAPTGABRPGABRDGABRA1GABRB1
	SCHEMBL3714696	0.83	MAPT (0.43)	MAPTGABRPGABRDGABRA1GABRB1
	SCHEMBL4568328	0.81	MAPK13 (0.38)	MAPTCNR1GRM5TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.