Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | STAT3 | P40763 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4568355 | 0.94 | ALDH1A1 (0.46) | ALDH1A1NPSR1LMNATSHRL3MBTL1 | |
| SCHEMBL31744674 | 0.88 | ALDH1A1 (0.59) | ALDH1A1NPSR1LMNATSHRL3MBTL1 | |
| SCHEMBL4568354 | 0.84 | MAPT (0.49) | ALDH1A1SMN1; SMN2KDM4EMEN1MAPT | |
| SCHEMBL4202989 | 0.83 | AAK1 (0.43) | ALDH1A1LMNAL3MBTL1KDM4EMEN1 | |
| SCHEMBL2792741 | 0.83 | ALDH1A1 (0.46) | ALDH1A1NPSR1LMNATSHRL3MBTL1 | |
| SCHEMBL15834220 | 0.82 | ALDH1A1 (0.45) | ALDH1A1NPSR1LMNATSHRL3MBTL1 | |
| SCHEMBL15818528 | 0.81 | KDM4E (0.49) | ALDH1A1NPSR1LMNATSHRL3MBTL1 | |
| SCHEMBL9731377 | 0.80 | SMN1; SMN2 (0.51) | ALDH1A1NPSR1LMNATSHRSMN1; SMN2 | |
| SCHEMBL8760722 | 0.80 | ALDH1A1 (0.40) | ALDH1A1KDM4EMEN1MAPTKMT2A | |
| SCHEMBL4568378 | 0.79 | ALDH1A1 (0.44) | ALDH1A1NPSR1LMNATSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122931-A1 | INDOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2012-05-17 | — | — | US | disclosed |
| US-20120122931-A1 | INDOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122931-A1 | INDOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | PTGER1, CYSLTR1, LTB4R | ALDH1A1 422/4885NPSR1 27/4885LMNA 4472/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.