Nipecotic Acid

Nipecotic Acid

SCHEMBL456856

O=C(O)C1CCCNC1.O=C(O)C1CCCNC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A1 P30531 3/20 1.00
TSHR P16473 2/20 1.00
SLC6A11 P48066 2/20 1.00
SLC6A13 Q9NSD5 2/20 1.00
LMNA P02545 1/20 1.00
SMN1; SMN2 Q16637 1/20 1.00
KMT2A Q03164 2/20 0.65
KDM4E B2RXH2 1/20 0.65
MAPT P10636 1/20 0.65
ATM Q13315 1/20 0.65
CYP2D6 P10635 1/20 0.65
NOS2 P35228 1/20 0.54
GABRA5 P31644 2/20 0.52
GABRB2 P47870 2/20 0.52
GABRP O00591 1/20 0.52
GABRD O14764 1/20 0.52
GABRA1 P14867 1/20 0.52
GABRB1 P18505 1/20 0.52
GABRG2 P18507 1/20 0.52
GABRB3 P28472 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
(R)-Nipecotic Acid SCHEMBL520075 1.00
Nipecotic Acid SCHEMBL85677 1.00
(S)-Nipecotic Acid SCHEMBL254683 1.00
(R)-Nipecotic Acid SCHEMBL29880539 1.00
Nipecotic Acid SCHEMBL15971488 0.98 SLC6A1 (0.95) SLC6A1TSHRSLC6A11SLC6A13LMNA
Nipecotic Acid SCHEMBL193736 0.98 SLC6A1 (0.95) SLC6A1TSHRSLC6A11SLC6A13LMNA
(R)-Nipecotic Acid SCHEMBL20562073 0.98 SLC6A1 (0.95) SLC6A1TSHRSLC6A11SLC6A13LMNA
Nipecotic Acid SCHEMBL17743427 0.98 SLC6A1 (0.95) SLC6A1TSHRSLC6A11SLC6A13LMNA
(S)-Nipecotic Acid SCHEMBL193735 0.98 SLC6A1 (0.95) SLC6A1TSHRSLC6A11SLC6A13LMNA
Nipecotic Acid SCHEMBL28212423 0.98 SLC6A1 (0.95) SLC6A1TSHRSLC6A11SLC6A13LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119264123-A Antagonists of T2R54, compositions thereof and uses thereof 弗门尼舍公司 2025-01-07 CN disclosed
CN-113194742-B Antagonists of T2R54, compositions thereof and uses thereof 弗门尼舍公司 2024-09-27 CN disclosed
WO-2018128828-A1 NOVEL HEPCIDIN MIMETICS AND USES THEREOF BAYER HEALTHCARE LLC (US) 2018-07-12 WO disclosed