⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Nipecotic Acid SCHEMBL456856 | 1.00 | SLC6A1 (1.00) | — | |
| Nipecotic Acid SCHEMBL85677 | 1.00 | — | — | |
| (S)-Nipecotic Acid SCHEMBL254683 | 1.00 | — | — | |
| (R)-Nipecotic Acid SCHEMBL29880539 | 1.00 | — | — | |
| Nipecotic Acid SCHEMBL15971488 | 0.98 | SLC6A1 (0.95) | — | |
| Nipecotic Acid SCHEMBL193736 | 0.98 | SLC6A1 (0.95) | — | |
| (R)-Nipecotic Acid SCHEMBL20562073 | 0.98 | SLC6A1 (0.95) | — | |
| Nipecotic Acid SCHEMBL17743427 | 0.98 | SLC6A1 (0.95) | — | |
| (S)-Nipecotic Acid SCHEMBL193735 | 0.98 | SLC6A1 (0.95) | — | |
| Nipecotic Acid SCHEMBL28212423 | 0.98 | SLC6A1 (0.95) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 589 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341008-B1 | PEPTIDES BINDING TO BFL-1 | DANA FARBER CANCER INST INC (US) | 2026-04-15 | — | — | EP | claimed |
| US-12466853-B2 | Selective targeting of apoptosis proteins by structurally-stabilized and/or cysteine-reactive NOXA peptides | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2025-11-11 | — | — | US | claimed |
| US-11834520-B2 | Selective targeting of apoptosis proteins by structurally-stabilized and/or cysteine-reactive NOXA peptides | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2023-12-05 | — | — | US | claimed |
| CN-115260046-A | Abietate compound and preparation method and application thereof | 贵州大学 | 2022-11-01 | — | — | CN | claimed |
| CN-115141208-A | Podophyllotoxin compound containing various ester group structures and preparation method and application thereof | 贵州大学 | 2022-10-04 | — | — | CN | claimed |
| US-20220169688-A1 | SELECTIVE TARGETING OF UBIQUITIN- AND UBIQUITIN-LIKE E1-ACTIVATING ENZYMES BY STRUCTURALLY-STABILIZED PEPTIDES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2022-06-02 | — | — | US | claimed |
| EP-3962933-A1 | SELECTIVE TARGETING OF UBIQUITIN- AND UBIQUITIN-LIKE E1-ACTIVATING ENZYMES BY STRUCTURALLY-STABILIZED PEPTIDES | Dana-Farber Cancer Institute, Inc. (US) | 2022-03-09 | — | — | EP | claimed |
| CN-106008459-B | The preparation method of one koji Ge Lieting | 山东四环药业股份有限公司 | 2018-07-13 | — | — | CN | claimed |
| WO-2016029146-A1 | SPECIFIC INHIBITORS OF METHIONYL-TRNA SYNTHETASE | UNIVERSITY OF WASHINGTON (US) | 2016-02-25 | — | — | WO | claimed |
| US-8809326-B2 | Isoquinolinone Rho kinase inhibitors | AERIE PHARMACEUTICALS, INC. (US) | 2014-08-19 | — | — | US | claimed |
| US-20080161297-A1 | e.g. N-(7-Chloro-1-oxo-1,2-dihydro-isoquinolin-6-yl)-2-dimethylamino-2-phenyl-acetamide; hypertension, atherosclerosis, restenosis, stroke, heart failure, coronary vasospasm, cerebral vasospasm, ischemia/reperfusion injury, pulmonary hypertension, angina, myocardial infarction, | ALCON INC. (CH) | 2008-07-03 | — | — | US | claimed |
| EP-1932852-A1 | Novel taxane related peptides and uses thereof | Campiani, Giuseppe (IT) | 2008-06-18 | — | — | EP | claimed |
| WO-2008036540-A2 | RHO KINASE INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2008-03-27 | — | — | WO | claimed |
| US-20070185128-A1 | Compounds and compositions for treating obesity | NOVO NORDISK A/S (DK) | 2007-08-09 | — | — | US | claimed |
| WO-2006071079-A1 | QUINAZOLINE DERIVATIVES FOR INHIBITING CANCER CELL GROWTH AND METHOD FOR THE PREPARATION THEREOF | HANMI PHARM. CO., LTD. (KR) | 2006-07-06 | — | — | WO | claimed |
| CN-1225471-C | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 2005-11-02 | — | — | CN | claimed |
| US-6350767-B1 | GROWTH HORMONE RELEASE STIMULANT | NOVO NORDISK A/S (DK) | 2002-02-26 | — | — | US | claimed |
| CN-1176645-A | Compounds with growth hormone releasing properties | NOVO NORDISK AS (DK) | 1998-03-18 | — | — | CN | claimed |
| EP-0805816-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1997-11-12 | — | — | EP | claimed |
| WO-1996022997-A1 | COMPOUNDS WITH GROWTH HORMONE RELEASING PROPERTIES | NOVO NORDISK A/S (DK) | 1996-08-01 | — | — | WO | claimed |