SCHEMBL4568646

SCHEMBL4568646

Cc1cccc(Nc2nc(Nc3cccc(C)c3)nc(Nc3cccc(C=O)c3)n2)c1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NFKB1 P19838 1/20 0.58
KCNH3 Q9ULD8 1/20 0.54
POLB P06746 2/20 0.52
SLC2A1 P11166 1/20 0.51
MAPT P10636 4/20 0.50
TP53 P04637 3/20 0.50
HTT P42858 1/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA9 Q16790 1/20 0.50
LMNA P02545 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.49
TNNI3K Q59H18 1/20 0.48
NPC1 O15118 1/20 0.48
RAB9A P51151 1/20 0.48
NOD1 Q9Y239 1/20 0.48
NPSR1 Q6W5P4 1/20 0.47
AURKA O14965 1/20 0.47
ABL1 P00519 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13401823 0.89 NFKB1 (0.56) NFKB1KCNH3POLBSLC2A1MAPT
SCHEMBL17018657 0.87 IDH2 (0.49) NFKB1KCNH3POLBSLC2A1MAPT
SCHEMBL30240628 0.85 NFKB1 (0.76) NFKB1KCNH3POLBSLC2A1MAPT
SCHEMBL762506 0.85 NFKB1 (0.76) NFKB1KCNH3POLBSLC2A1MAPT
SCHEMBL12154944 0.83 NFKB1 (0.56) NFKB1KCNH3POLBSLC2A1MAPT
SCHEMBL29953075 0.81 AURKA (0.54) NFKB1MAPTTP53SMN1; SMN2TNNI3K
SCHEMBL9185907 0.80 NPSR1 (0.58) NFKB1MAPTHTTNPC1RAB9A
SCHEMBL821689 0.80 NFKB1 (0.69) NFKB1KCNH3POLBSLC2A1MAPT
SCHEMBL4544851 0.80 KCNH3 (0.77) NFKB1KCNH3POLBSLC2A1MAPT
SCHEMBL4544806 0.80 NFKB1 (0.69) NFKB1KCNH3POLBSLC2A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120236235-A1 LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-09-20 US disclosed
US-20120120348-A1 VA-MODE LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2012-05-17 US disclosed
US-20110128473-A1 VA MODE LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-06-02 US disclosed
US-20110128478-A1 POLARIZING PLATE, LIQUID CRYSTAL DISPLAY, AND METHOD OF MANUFACTURING PROTECTIVE FILM FOR POLARIZING PLATE KONICA MINOLTA OPTO, INC. (JP) 2011-06-02 US disclosed
US-20110075080-A1 RETARDATION FILM, METHOD OF PRODUCING THE RETARDATION FILM, AND POLARIZING PLATE AND LIQUID-CRYSTAL DISPLAY DEVICE HAVING THE SAME FUJIFILM CORPORATION (JP) 2011-03-31 US disclosed
US-20110058131-A1 VA-MODE LIQUID-CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2011-03-10 US disclosed
US-20100220272-A1 LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2010-09-02 US disclosed
US-20100020273-A1 POLYMER FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2010-01-28 US disclosed
US-7611760-B2 Cellulose acylate film, optical compensation film, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2009-11-03 US disclosed
US-20090066887-A1 Polymer Film, Polarizing Plate Protective Film, Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2009-03-12 US disclosed
US-20080213511-A1 Optical compensation film, process for producing optical compensation film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-09-04 US disclosed