Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 2/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.46 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.45 |
| ▸ | LTA4H | P09960 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4568916 | 0.89 | MAOB (0.54) | MAOBKMT2AGPBAR1CYSLTR1TSHR | |
| SCHEMBL4568925 | 0.88 | MAOB (0.53) | MAOBKMT2AGPBAR1CYSLTR1TSHR | |
| SCHEMBL4568917 | 0.88 | MAOB (0.53) | MAOBKMT2AGPBAR1CYSLTR1TSHR | |
| SCHEMBL4568938 | 0.87 | MAOB (0.69) | MAOBKMT2AGPBAR1CYSLTR1BCHE | |
| SCHEMBL4568922 | 0.86 | MAOB (0.51) | MAOBKMT2AGPBAR1CYSLTR1TSHR | |
| SCHEMBL10796629 | 0.83 | KMT2A (0.61) | KMT2AGPBAR1CYSLTR1TSHRPLA2G4B | |
| SCHEMBL12703452 | 0.82 | KDM4E (0.48) | MAOBKMT2AGPBAR1CYSLTR1TSHR | |
| SCHEMBL14448286 | 0.82 | KDM4E (0.48) | MAOBKMT2AGPBAR1CYSLTR1TSHR | |
| SCHEMBL3158759 | 0.81 | TSHR (0.64) | MAOBTSHRBCHELMNAL3MBTL1 | |
| SCHEMBL4568905 | 0.80 | KMT2A (0.54) | MAOBKMT2AGPBAR1CYSLTR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122938-A1 | Alkoxy Compounds for Disease Treatment | ACUCELA INC. (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122938-A1 | Alkoxy Compounds for Disease Treatment | ALDH1A2, CLN6, AGER | MAOB 318/4885KMT2A 3103/4885GPBAR1 294/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.