SCHEMBL456942

SCHEMBL456942

CCc1[c]ccc(Cl)c1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL206972 0.83 MEN1 (0.33)
SCHEMBL1925068 0.81 MEN1 (0.33)
SCHEMBL3595125 0.79 KMT2A (0.41)
SCHEMBL3939489 0.79
SCHEMBL1418990 0.78 TAAR1 (0.41)
SCHEMBL750293 0.78 ALOX5 (0.38)
SCHEMBL5328557 0.78 MEN1 (0.37)
SCHEMBL9008004 0.77
SCHEMBL9529183 0.77
SCHEMBL27923023 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 213 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11807620-B2 Quinazolinone compounds and related compounds Plexium, Inc. (US) 2023-11-07 US claimed
CN-105593214-B Method for synthesizing N-benzyl-N-cyclopropyl-1H-pyrazole-4-formamide derivative 拜耳作物科学股份公司 2018-05-29 CN claimed
CN-103097364-B Spiro-piperidine derivatives as S1P modulators ABBOTT HEALTHCARE PRODUCTS B.V. (NL) 2015-11-25 CN claimed
US-8642647-B2 N1-benzo[1,3]dioxol-5-ylmethyl-N2-substituted biguanide derivative, preparation method thereof, and pharmaceutical composition containing same HANALL BIOPHARMA CO., LTD. (KR) 2014-02-04 US claimed
CN-101600700-B Novel 2-amino oxazolines as TAAR1 ligands for CNS disorders HOFFMANN LA ROCHE 2013-08-21 CN claimed
CN-103097364-A Spiro-piperidine derivatives as S1P modulators ABBOTT HEALTHCARE PRODUCTS BV 2013-05-08 CN claimed
EP-2513064-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING BIOFILMS Katholieke Universiteit Leuven, K.U. Leuven R&D (BE) 2012-10-24 EP claimed
US-20110207810-A1 N1-BENZO[1,3]DIOXOL-5-YLMETHYL-N2-SUBSTITUTED BIGUANIDE DERIVATIVE, PREPARATION METHOD THEREOF, AND PHARMACEUTICAL COMPOSITION CONTAINING SAME HANALL BIOPHARMA CO., LTD. (KR) 2011-08-25 US claimed
WO-2011080132-A2 COMPOUNDS, COMPOSITIONS AND METHODS FOR CONTROLLING BIOFILMS KATHOLIEKE UNIVERSITEIT LEUVEN, K.U. LEUVEN R&D (BE) 2011-07-07 WO claimed
US-6887877-B2 Compounds and methods for the treatment or prevention of Flavivirus infections VIROCHEM PHARMA INC. (CA) 2005-05-03 US claimed
EP-0407854-B1 1-Halogen-vinylazoles and fungicides containing them BASF AG (DE) 1994-06-15 EP claimed
US-11807620-B2 Quinazolinone compounds and related compounds Plexium, Inc. (US) 2023-11-07 US disclosed
EP-3183250-B1 PROCESS FOR PREPARING CRYSTALLINE ORGANIC SEMICONDUCTOR MATERIAL CLAP CO LTD (KR) 2023-10-04 EP disclosed
US-20230303608-A1 DITHIOLENE METAL COMPLEXES BASF SCHWEIZ AG (CH) 2023-09-28 US disclosed
EP-4182395-A1 DITHIOLENE METAL COMPLEXES BASF SE (DE) 2023-05-24 EP disclosed
US-4112024-A PESTICIDES EXXON RESEARCH & ENGINEERING CO. (US) 1978-09-05 US disclosed
US-4099007-A N,N-SUBSTITUTED 2,4,5-TRIKETOIMIDAZOLIDINES AND A PROCESS FOR THEIR PREPARATION HOECHST AKTIENGESELLSCHAFT (DE) 1978-07-04 US disclosed
US-4003939-A PESTICIDES EXXON RESEARCH AND ENGINEERING COMPANY (US) 1977-01-18 US disclosed
US-3973013-A Substituted S-carboxymethyl-(thiono)-(di)-thiol-phosphonic acid esters and ester-amides and insecticidal composition and method BAYER AKTIENGESELLSCHAFT (DT) 1976-08-03 US disclosed
US-3931218-A HYPOGLYCEMIC ANTIRESERPINE, ANTIULCER, OGENIC, ANTIARRHYTHMIA AMERICAN HOME PRODUCTS CORPORATION (US) 1976-01-06 US disclosed