SCHEMBL206972

SCHEMBL206972

CCCc1[c]ccc(Cl)c1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3595125 0.88 KMT2A (0.41) MEN1KMT2A
SCHEMBL5328557 0.86 MEN1 (0.37) MEN1KMT2A
SCHEMBL9330220 0.85 KCNH2 (0.38) MEN1KMT2A
SCHEMBL25066 0.85 KCNH2 (0.38) MEN1KMT2A
SCHEMBL456942 0.83
SCHEMBL8178262 0.80 PNMT (0.32)
SCHEMBL5792075 0.79 TAAR1 (0.44)
SCHEMBL27794927 0.79
SCHEMBL7482400 0.79 TAAR1 (0.49) MEN1KMT2A
SCHEMBL1925068 0.78 MEN1 (0.33) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 321 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2280966-A1 AZABICYCLO [3.2.1]OCTYL DERIVATIVES AS 11 BETA-HSD1 MODULATORS Exelixis, Inc. (US) 2011-02-09 EP claimed
WO-2009114173-A1 AZABICYCLO [3. 2. I] OCTYL DERIVATIVES AS 11 BETA-HSDL MODULATORS EXELIXIS, INC. (US) 2009-09-17 WO claimed
WO-2024129637-A1 DECREASING TRIBOELECTRIC CHARGING OF, AND/OR REACTOR FOULING BY, POLYOLEFIN PARTICLES UNIVATION TECHNOLOGIES, LLC (US) 2024-06-20 WO disclosed
US-11384164-B2 Methods and systems for olefin polymerization UNIVATION TECHNOLOGIES, LLC (US) 2022-07-12 US disclosed
EP-3283532-B1 METHODS AND SYSTEMS FOR OLEFIN POLYMERIZATION UNIVATION TECH LLC (US) 2022-05-18 EP disclosed
US-11117991-B2 Methods for operating a polymerization reactor UNIVATION TECHNOLOGIES, LLC (US) 2021-09-14 US disclosed
CN-107531839-B Method for operating a polymerization reactor 尤尼威蒂恩技术有限责任公司 2021-05-25 CN disclosed
CN-107531827-B Process and system for olefin polymerization 尤尼威蒂恩技术有限责任公司 2021-04-23 CN disclosed
US-20200299418-A1 METHODS AND SYSTEMS FOR OLEFIN POLYMERIZATION UNIVATION TECHNOLOGIES, LLC (US) 2020-09-24 US disclosed
US-10711072-B2 Methods and systems for olefin polymerization UNIVATION TECHNOLOGIES, LLC (US) 2020-07-14 US disclosed
EP-2750797-B1 METHODS OF PREPARING A CATALYST SYSTEM UNIVATION TECH LLC (US) 2020-04-01 EP disclosed
US-4028419-A PROSTAGLANDINS THE UPJOIN COMPANY (US) 1977-06-07 US disclosed
US-4028350-A ANTIINFLAMMATORY AGENTS THE UPJOHN COMPANY (US) 1977-06-07 US disclosed
US-4026909-A PROSTAGLANDINS THE UPJOHN COMPANY (US) 1977-05-31 US disclosed
US-4018803-A 13,14-Didehydro-PG3 compounds THE UPJOHN COMPANY (US) 1977-04-19 US disclosed
US-4016184-A PROSTAGLANDINS, BLOOD PLATELET AGGREGATION INHIBITORS THE UPJOHN COMPANY (US) 1977-04-05 US disclosed
US-4013695-A PROSTAGLANDINS, HYPOTENSIVES, OXYTOCICS, ANTISECRETORY AND ANTIULCER AGENTS, REPRODUCTION CONTROL THE UPJOHN COMPANY (US) 1977-03-22 US disclosed
US-4001300-A ANTIULCER, DECONGESTANT, LABOR INDUCER, WOUND HEALER THE UPJOHN COMPANY (US) 1977-01-04 US disclosed
US-3974146-A Cyanolpoxy intermediates for prostaglandins and process for preparing same THE UPJOHN COMPANY (US) 1976-08-10 US disclosed
US-3931279-A 5-Oxa prostaglandin F2.sub.α analogs THE UPJOHN COMPANY (US) 1976-01-06 US disclosed