SCHEMBL456949

SCHEMBL456949

NC(Cc1nccs1)C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FDPS P14324 1/20 0.53
GRIA1 P42261 3/20 0.50
GRIA2 P42262 3/20 0.50
GRIA3 P42263 3/20 0.50
GRIA4 P48058 3/20 0.50
GRIK1 P39086 2/20 0.50
GRIK2 Q13002 1/20 0.50
GRIK3 Q13003 1/20 0.50
GRIK4 Q16099 1/20 0.50
GRIK5 Q16478 1/20 0.50
HSD17B10 Q99714 2/20 0.44
SLC7A5 Q01650 3/20 0.43
PKM P14618 2/20 0.43
ALPI P09923 1/20 0.43
PTGS1 P23219 1/20 0.43
XIAP P98170 1/20 0.43
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 2/20 0.40
USP2 O75604 2/20 0.40
SLC6A3 Q01959 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL156953 1.00 FDPS (0.53) FDPSGRIA1GRIA2GRIA3GRIA4
SCHEMBL5514921 1.00 FDPS (0.53) FDPSGRIA1GRIA2GRIA3GRIA4
SCHEMBL6385699 0.86 FDPS (0.53) FDPSGRIA1GRIA2GRIA3GRIA4
SCHEMBL21299172 0.86 FDPS (0.53) FDPSGRIA1GRIA2GRIA3GRIA4
SCHEMBL6820530 0.83 GRB2 (0.42) FDPSGRIA1GRIA2GRIA3GRIA4
Ibotenic Acid SCHEMBL2219171 0.81 GRM1 (0.58) FDPSGRIA1GRIA2GRIA3GRIA4
Ibotenic Acid SCHEMBL2219174 0.81 GRM1 (0.58) FDPSGRIA1GRIA2GRIA3GRIA4
SCHEMBL5218566 0.80 FDPS (0.47) FDPSPKMCYP3A4MEN1ALDH1A1
SCHEMBL2059143 0.80 FDPS (0.47) FDPSPKMCYP3A4MEN1ALDH1A1
SCHEMBL1768354 0.80 GRIN3B (0.41) FDPSGRIA1GRIA2GRIA3GRIA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 619 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240197896-A1 SYNTHETIC PEPTIDE SHUTTLE AGENT BIOCONJUGATES FOR INTRACELLULAR CARGO DELIVERY FELDAN BIO INC. (CA) 2024-06-20 US claimed
CN-117750978-A Synthetic peptide shuttle bioconjugates for intracellular cargo delivery 费尔丹生物公司 2024-03-22 CN claimed
US-20230399661-A1 SHUTTLE AGENT PEPTIDES OF MINIMAL LENGTH AND VARIANTS THEREOF ADAPTED FOR TRANSDUCTION OF CAS9-RNP AND OTHER NUCLEOPROTEIN CARGOS FELDAN BIO INC. (CA) 2023-12-14 US claimed
US-20230383291-A1 PEPTIDE-BASED TRANSDUCTION OF NON-ANIONIC POLYNUCLEOTIDE ANALOGS FOR GENE EXPRESSION MODULATION FELDAN BIO INC. (CA) 2023-11-30 US claimed
EP-4232590-A1 SHUTTLE AGENT PEPTIDES OF MINIMAL LENGTH AND VARIANTS THEREOF ADAPTED FOR TRANSDUCTION OF CAS9-RNP AND OTHER NUCLEOPROTEIN CARGOS Feldan Bio Inc. (CA) 2023-08-30 EP claimed
CN-116615227-A Minimum length shuttle peptide suitable for transduction of Cas9-RNP and other nucleoprotein loads and variants thereof 费尔丹生物公司 2023-08-18 CN claimed
CN-116615205-A Peptide-based transduction of non-anionic polynucleotide analogs for modulation of gene expression 费尔丹生物公司 2023-08-18 CN claimed
US-20220204561-A1 PEPTIDE-BASED NON-PROTEINACEOUS CARGO DELIVERY FELDAN BIO INC. (CA) 2022-06-30 US claimed
WO-2022082315-A1 SHUTTLE AGENT PEPTIDES OF MINIMAL LENGH AND VARIANTS THEREOF ADAPTED FOR TRANSDUCTION OF CAS9-RNP AND OTHER NUCLEOPROTEIN CARGOS FELDAN BIO INC. (CA) 2022-04-28 WO claimed
CN-114008210-A Peptide-based non-protein cargo delivery 费尔丹生物公司 2022-02-01 CN claimed
US-5589277-A INK JET PRINTING, AQUEOUS INKS, FAST DRYING XEROX CORPORATION (US) 1996-12-31 US claimed
WO-1995030687-A1 NEUROKININE (TACHYKININE) ANTAGONISTS BOEHRINGER INGELHEIM KG (DE) 1995-11-16 WO claimed
EP-0667246-A1 Recording sheets containing amino acids, hydroxy acids, and polycarboxyl compounds XEROX CORPORATION (US) 1995-08-16 EP claimed
EP-0652229-A2 Oligopeptides with fungicidal activity ISAGRO S.p.A. (IT) 1995-05-10 EP claimed
WO-1995001188-A1 POLYVALENT PEPTIDE PHARMACEUTICAL APPLICATIONS RHOMED INCORPORATED (US) 1995-01-12 WO claimed
EP-0610487-A1 NEW AMINOACID DERIVATES, PROCESS FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS BOEHRINGER INGELHEIM KG (DE) 1994-08-17 EP claimed
WO-1994005693-A1 NEW AMINOACID DERIVATES, PROCESS FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS BOEHRINGER INGELHEIM KG (DE) 1994-03-17 WO claimed
US-4393135-A GENETICALLY ENGINEERED ESCHERICHIA AJINOMOTO COMPANY INCORPORATED (JP) 1983-07-12 US claimed
US-4388405-A ESCHERICHIA INCORPORATED WITH HYBRID PLASMID AJINOMOTO COMPANY INCORPORATED (JP) 1983-06-14 US claimed
EP-0030391-A2 Method for producing L-glutamic acid by fermentation and a method for producing a new microorganism AJINOMOTO CO., INC. (JP) 1981-06-17 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240197896-A1 SYNTHETIC PEPTIDE SHUTTLE AGENT BIOCONJUGATES FOR INTRACELLULAR CARGO DELIVERY SCAMP2, SLC7A1, NUMA1 FDPS 4606/4885GRIA1 2216/4885GRIA2 2569/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.