Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 12/20 | 0.40 |
| ▸ | TTK | P33981 | 7/20 | 0.36 |
| ▸ | KIT | P10721 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | CDK7 | P50613 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12467108 | 0.90 | TTK (0.36) | TTKKITPIM1FLT3CDK7 | |
| SCHEMBL457970 | 0.88 | TTK (0.44) | ERN1TTK | |
| SCHEMBL461988 | 0.81 | TTK (0.40) | TTK | |
| SCHEMBL457467 | 0.77 | TTK (0.40) | TTK | |
| SCHEMBL456371 | 0.76 | TTK (0.46) | ERN1TTK | |
| SCHEMBL12466791 | 0.76 | ERN1 (0.43) | ERN1TTK | |
| SCHEMBL459378 | 0.76 | TTK (0.57) | ERN1TTK | |
| SCHEMBL463285 | 0.76 | PDE4D (0.43) | TTKFLT3 | |
| SCHEMBL462359 | 0.75 | TTK (0.42) | TTK | |
| SCHEMBL456964 | 0.72 | TTK (0.36) | ERN1TTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614063-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | Bayer Intellectual Property GmbH (DE) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012032031-A1 | SUBSTITUTED IMIDAZOPYRIDAZINES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | WO | disclosed |