Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 2/20 | 0.42 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.36 |
| ▸ | TAS2R14 | Q9NYV8 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | LIMK2 | P53671 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1156624 | 0.90 | CHRM5 (0.43) | HTR6CHRM5MEN1LMNAKMT2A | |
| SCHEMBL1156488 | 0.89 | CHRM5 (0.36) | PTGDR2CHRM5ALDH1A1KMT2A | |
| SCHEMBL1156885 | 0.89 | PTGDR2 (0.40) | PTGDRPTGDR2PKMHTR6TAS2R14 | |
| SCHEMBL1156564 | 0.88 | LMNA (0.41) | PTGDR2HTR6PTGER2CHRM5MEN1 | |
| SCHEMBL4411754 | 0.88 | CHRM5 (0.42) | HTR6CHRM5MEN1LMNAKMT2A | |
| SCHEMBL4569678 | 0.84 | PTGDR (0.43) | PTGDRPTGDR2PKMTSHRHTR6 | |
| SCHEMBL1156789 | 0.83 | LMNA (0.39) | PTGDR2PKMTSHRCHRM5ALDH1A1 | |
| SCHEMBL1156756 | 0.83 | PTGER2 (0.38) | PTGDR2TSHRPTGER2ALDH1A1KMT2A | |
| SCHEMBL2418769 | 0.82 | HTR6 (0.37) | PTGDRPTGDR2PKMTSHRHTR6 | |
| Carbamic Acid SCHEMBL4791646 | 0.82 | PTGER2 (0.39) | TSHRPTGER2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2114917-A2 | PYRROLE COMPOUNDS | Takeda Pharmaceutical Company Limited (JP) | 2009-11-11 | — | — | EP | disclosed |
| WO-2008108380-A2 | PYRROLE COMPOUNDS | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2008-09-12 | — | — | WO | disclosed |