Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 1/20 | 0.43 |
| ▸ | PAK3 | O75914 | 1/20 | 0.31 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.31 |
| ▸ | PAK2 | Q13177 | 1/20 | 0.31 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4569947 | 0.75 | CHRNA7 (0.47) | CHRNA7 | |
| SCHEMBL24471039 | 0.75 | CHRNA7 (0.42) | CHRNA7 | |
| SCHEMBL38657978 | 0.74 | ASIC3 (0.39) | — | |
| SCHEMBL25588446 | 0.72 | CHRNA7 (0.36) | CHRNA7 | |
| SCHEMBL15999369 | 0.71 | CHRNA7 (0.44) | CHRNA7 | |
| SCHEMBL22545236 | 0.71 | CHRNA7 (0.44) | CHRNA7 | |
| SCHEMBL20890037 | 0.71 | CHRNA7 (0.38) | CHRNA7 | |
| SCHEMBL20890033 | 0.70 | CHRNA7 (0.37) | CHRNA7 | |
| SCHEMBL20890030 | 0.70 | CHRNA7 (0.35) | CHRNA7 | |
| SCHEMBL24823782 | 0.70 | CHRNA7 (0.43) | CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122679-A1 | MESOIONIC PESTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122679-A1 | MESOIONIC PESTICIDES | CHRM2, CHRM5, CHRM1 | CHRNA7 9/4885PAK3 4556/4885PAK1 4397/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.