Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.68 |
| ▸ | NPC1 | O15118 | 6/20 | 0.68 |
| ▸ | MAPT | P10636 | 6/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.68 |
| ▸ | POLB | P06746 | 3/20 | 0.68 |
| ▸ | PKM | P14618 | 3/20 | 0.68 |
| ▸ | TP53 | P04637 | 2/20 | 0.68 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.56 |
| ▸ | RELA | Q04206 | 2/20 | 0.56 |
| ▸ | TGFBR1 | P36897 | 5/20 | 0.56 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.56 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29496952 | 1.00 | RAB9A (0.68) | RAB9ANPC1MAPTSMN1; SMN2POLB | |
| SCHEMBL29496949 | 1.00 | RAB9A (0.68) | RAB9ANPC1MAPTSMN1; SMN2POLB | |
| SCHEMBL21451444 | 0.90 | NPC1 (0.56) | RAB9ANPC1MAPTSMN1; SMN2POLB | |
| SCHEMBL15188295 | 0.83 | TGFBR1 (0.57) | RAB9ANPC1MAPTSMN1; SMN2POLB | |
| SCHEMBL6600949 | 0.83 | RAB9A (0.54) | RAB9ANPC1MAPTSMN1; SMN2POLB | |
| SCHEMBL4035328 | 0.81 | MAPT (0.55) | RAB9ANPC1MAPTSMN1; SMN2POLB | |
| SCHEMBL3243762 | 0.79 | MAPT (0.53) | RAB9ANPC1MAPTSMN1; SMN2POLB | |
| SCHEMBL4134118 | 0.79 | NPC1 (0.65) | RAB9ANPC1MAPTSMN1; SMN2POLB | |
| SCHEMBL9739930 | 0.79 | NPC1 (0.54) | RAB9ANPC1MAPTSMN1; SMN2POLB | |
| SCHEMBL20380088 | 0.78 | KDM4E (0.59) | RAB9ANPC1MAPTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8637563-B2 | Non-peptide thrombopoietin receptor agonist in the treatment of cancer and pre-cancerous syndromes | GLAXOSMITHKLINE LLC (US) | 2014-01-28 | — | — | US | disclosed |
| US-20120122679-A1 | MESOIONIC PESTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-05-17 | — | — | US | disclosed |
| US-20120122679-A1 | MESOIONIC PESTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2012-05-17 | — | — | US | disclosed |
| WO-2011017334-A2 | MESOIONIC PESTICIDES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2011-02-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122679-A1 | MESOIONIC PESTICIDES | CHRM2, CHRM5, CHRM1 | RAB9A 1515/4885NPC1 3740/4885MAPT 4703/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.