SCHEMBL457045

SCHEMBL457045

CP(=O)(O)c1cccc2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACP3 P15309 3/20 0.48
PTK2B Q14289 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
CA12 O43570 1/20 0.44
CA2 P00918 1/20 0.44
MMP2 P08253 1/20 0.44
MMP9 P14780 1/20 0.44
MMP8 P22894 1/20 0.44
MMP14 P50281 1/20 0.44
CA14 Q9ULX7 1/20 0.44
PLK1 P53350 1/20 0.44
KDM4E B2RXH2 2/20 0.44
LMNA P02545 2/20 0.44
POLB P06746 1/20 0.44
ALDH1A1 P00352 2/20 0.41
CYP2A6 P11509 2/20 0.41
CYP1A2 P05177 2/20 0.41
MMP3 P08254 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
NR4A1 P22736 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL81300 0.83 ACP3 (0.52) ACP3PTK2BL3MBTL1CA12CA2
SCHEMBL31742347 0.83 ACP3 (0.52) ACP3PTK2BL3MBTL1CA12CA2
SCHEMBL339616 0.83 ACP3 (0.52) ACP3PTK2BL3MBTL1CA12CA2
SCHEMBL26023414 0.83 KDM4E (0.46) ACP3PTK2BL3MBTL1CA12CA2
SCHEMBL19743195 0.83 KDM4E (0.46) ACP3PTK2BL3MBTL1CA12CA2
SCHEMBL3787100 0.82 ESR1 (0.48) ACP3PTK2BL3MBTL1CA12CA2
Hydrochloric Acid SCHEMBL28699780 0.81 ACP3 (0.50) ACP3PTK2BL3MBTL1CA12CA2
SCHEMBL4203091 0.79 ACP3 (0.48) ACP3PTK2BL3MBTL1CA12CA2
Water SCHEMBL28995210 0.79 ACP3 (0.48) ACP3PTK2BL3MBTL1CA12CA2
Formaldehyde SCHEMBL3281282 0.79 PTK2B (0.52) ACP3PTK2BL3MBTL1CA12CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 74 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260098160-A1 WATER RESISTANCE FOR ORGANIC FACADES ROHM & HAAS (US) 2026-04-09 US claimed
CN-113518803-B Waterproof property of organic external wall 罗门哈斯公司 2023-09-15 CN claimed
EP-3941982-B1 WATER RESISTANCE FOR ORGANIC FACADES ROHM & HAAS (US) 2023-06-21 EP claimed
US-20220154010-A1 WATER RESISTANCE FOR ORGANIC FACADES ROHM AND HAAS COMPANY (US) 2022-05-19 US claimed
EP-3941982-A1 WATER RESISTANCE FOR ORGANIC FACADES Rohm and Haas Company (US) 2022-01-26 EP claimed
CN-113518803-A Water resistance of organic outer wall 罗门哈斯公司 2021-10-19 CN claimed
WO-2020197825-A1 WATER RESISTANCE FOR ORGANIC FACADES ROHM AND HAAS COMPANY (US) 2020-10-01 WO claimed
US-20260098160-A1 WATER RESISTANCE FOR ORGANIC FACADES ROHM & HAAS (US) 2026-04-09 US disclosed
US-12435222-B2 Water resistance for organic facades ROHM AND HAAS COMPANY (US) 2025-10-07 US disclosed
EP-4359478-B1 SYSTEMS AND METHODS FOR COATING MULTI-LAYERED COATED METAL SUBSTRATES PRC DESOTO INT INC (US) 2025-08-06 EP disclosed
US-12221554-B2 Electrodepositable coating composition PRC-DESOTO INTERNATIONAL, INC. (US) 2025-02-11 US disclosed
US-20240270985-A1 SYSTEMS AND METHODS FOR COATING MULTI-LAYERED COATED METAL SUBSTRATES PRC-DESOTO INTERNATIONAL, INC. (US) 2024-08-15 US disclosed
EP-4359478-A1 SYSTEMS AND METHODS FOR COATING MULTI-LAYERED COATED METAL SUBSTRATES PRC-Desoto International, Inc. (US) 2024-05-01 EP disclosed
US-20110008625-A1 ELECTRODEPOSITION COATINGS INCLUDING A LANTHANIDE SERIES ELEMENT FOR USE OVER ALUMINUM SUBSTRATES PPG INDUSTRIES OHIO, INC. 2011-01-13 US disclosed
EP-2178942-A1 ELECTRODEPOSITION COATINGS FOR USE OVER ALUMINUM SUBSTRATES PPG Industries Ohio, Inc. (US) 2010-04-28 EP disclosed
EP-2178991-A1 STABILIZING AQUEOUS ANIONIC RESINOUS DISPERSIONS WITH CHELATING AGENTS PPG Industries Ohio, Inc. (US) 2010-04-28 EP disclosed
WO-2009023687-A1 STABILIZING AQUEOUS ANIONIC RESINOUS DISPERSIONS WITH CHELATING AGENTS PPG INDUSTRIES OHIO, INC. (US) 2009-02-19 WO disclosed
WO-2009023690-A1 ELECTRODEPOSITION COATINGS FOR USE OVER ALUMINUM SUBSTRATES PPG INDUSTRIES OHIO, INC. (US) 2009-02-19 WO disclosed
US-20090045065-A1 STABILIZING AQUEOUS ANIONIC RESINOUS DISPERSIONS WITH CHELATING AGENTS PPG INDUSTRIES OHIO, INC. (US) 2009-02-19 US disclosed
US-20090045071-A1 ELECTRODEPOSITION COATINGS FOR USE OVER ALUMINUM SUBSTRATES PPG INDUSTRIES OHIO, INC. (US) 2009-02-19 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260098160-A1 WATER RESISTANCE FOR ORGANIC FACADES ERG, LATS2, FTO ACP3 2266/4885PTK2B 1830/4885L3MBTL1 3822/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.