SCHEMBL4570500

SCHEMBL4570500

CNC(=O)c1ccc2c(c1)C(=O)N(c1c(C)cc(C)c(C)c1C)C2=O

nearest known ligand 0.47

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 2/20 0.45
▸ KMT2A Q03164 2/20 0.45
▸ POLB P06746 1/20 0.45
▸ NPSR1 Q6W5P4 1/20 0.44
▸ ANPEP P15144 1/20 0.42
▸ DPP4 P27487 1/20 0.42
▸ PDCD1 Q15116 1/20 0.42
▸ CD274 Q9NZQ7 1/20 0.42
▸ S100B P04271 1/20 0.40
▸ ALDH1A1 P00352 2/20 0.40
▸ CA12 O43570 1/20 0.40
▸ CA1 P00915 1/20 0.40
▸ CA9 Q16790 1/20 0.40
▸ PTPN7 P35236 1/20 0.40
▸ PTPN22 Q9Y2R2 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15826863 0.82 APEX1 (0.44) NPSR1ANPEPDPP4ALDH1A1CA12
SCHEMBL13155491 0.78 CA9 (0.65) MEN1KMT2APOLBNPSR1ALDH1A1
SCHEMBL12405518 0.77 NPSR1 (0.73) MEN1KMT2ANPSR1S100BALDH1A1
SCHEMBL15448519 0.77 APEX1 (0.40) NPSR1ANPEPDPP4ALDH1A1CA12
SCHEMBL10098927 0.75 ALDH1A1 (0.61) MEN1KMT2APOLBALDH1A1
SCHEMBL10098943 0.75 CA12 (0.64) MEN1KMT2AS100BALDH1A1CA12
SCHEMBL10098928 0.75 CA9 (0.60) MEN1KMT2APOLBNPSR1ALDH1A1
SCHEMBL15397059 0.74 NPSR1 (0.57) MEN1KMT2APOLBNPSR1S100B
SCHEMBL12405517 0.74 MAPK1 (0.62) MEN1KMT2APOLBNPSR1S100B
SCHEMBL9925389 0.73 MEN1 (0.50) MEN1KMT2APOLBNPSR1PDCD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9383665-B2 Ammonium alkylphosphate containing intermediate transfer members XEROX CORPORATION (US) 2016-07-05 — — US disclosed
US-8906513-B2 Fuser member XEROX CORPORATION (US) 2014-12-09 — — US disclosed
US-8577267-B2 Transparent intermediate transfer members containing zinc oxide, polyarylsulfone, and polyetheramine XEROX CORPORATION (US) 2013-11-05 — — US disclosed
US-20130149639-A1 AMMONIUM ALKYLPHOSPHATE CONTAINING INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2013-06-13 — — US disclosed
US-8409719-B2 Ammonium alkylphosphate containing intermediate transfer members XEROX CORPORATION (US) 2013-04-02 — — US disclosed
US-8366969-B2 Phosphate ester polyamideimide mixture containing intermediate transfer members XEROX CORPORATION (US) 2013-02-05 — — US disclosed
US-20130009104-A1 AMMONIUM ALKYLPHOSPHATE CONTAINING INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2013-01-10 — — US disclosed
US-8329367-B2 Polyamideimide containing photoconductors XEROX CORPORATION (US) 2012-12-11 — — US disclosed
US-8252420-B2 Polyamideimide polybenzimidazole containing intermediate transfer members XEROX CORPORATION (US) 2012-08-28 — — US disclosed
US-20120183783-A1 POLYAMIDEIMIDE POLYBENZIMIDAZOLE CONTAINING INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2012-07-19 — — US disclosed
US-20120148816-A1 FUSER MEMBER XEROX CORPORATION (US) 2012-06-14 — — US disclosed
US-20120119160-A1 TRANSPARENT INTERMEDIATE TRANSFER MEMBERS CONTAINING ZINC OXIDE, POLYARYLSULFONE, AND POLYETHERAMINE XEROX CORPORATION (US) 2012-05-17 — — US disclosed
US-20120049122-A1 PHOSPHATE ESTER POLYAMIDEIMIDE MIXTURE CONTAINING INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2012-03-01 — — US disclosed
US-20110183245-A1 POLYAMIDEIMIDE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2011-07-28 — — US disclosed
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