SCHEMBL4570503

SCHEMBL4570503

CNC(=O)c1ccc2c(c1)C(=O)N(C(C)(C)c1cccc(C(C)(C)C)c1)C2=O

nearest known ligand 0.50

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ MEN1 O00255 3/20 0.50
▸ KMT2A Q03164 3/20 0.50
▸ RAB9A P51151 6/20 0.49
▸ NPC1 O15118 4/20 0.49
▸ POLB P06746 4/20 0.49
▸ GFER P55789 1/20 0.49
▸ ALDH1A1 P00352 3/20 0.45
▸ TP53 P04637 1/20 0.45
▸ MAPK1 P28482 1/20 0.45
▸ MAPT P10636 1/20 0.44
▸ HDAC8 Q9BY41 2/20 0.43
▸ HDAC6 Q9UBN7 2/20 0.43
▸ CA9 Q16790 2/20 0.43
▸ CA12 O43570 1/20 0.43
▸ CA1 P00915 1/20 0.43
▸ S100B P04271 1/20 0.43
▸ SMN1; SMN2 Q16637 2/20 0.43
▸ HDAC3 O15379 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13012944 0.85 RAB9A (0.48) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL10120025 0.75 HDAC8 (0.59) MEN1KMT2APOLBALDH1A1HDAC8
SCHEMBL12227214 0.73 MEN1 (0.45) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL12227249 0.73 MEN1 (0.47) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL10098927 0.72 ALDH1A1 (0.61) MEN1KMT2APOLBALDH1A1
SCHEMBL4572442 0.71 MEN1 (0.41) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL17897619 0.70 POLB (0.54) MEN1KMT2ARAB9ANPC1POLB
SCHEMBL10098943 0.70 CA12 (0.64) MEN1KMT2ARAB9AGFERALDH1A1
SCHEMBL12405517 0.68 MAPK1 (0.62) MEN1KMT2ARAB9APOLBALDH1A1
SCHEMBL7604337 0.68 RAB9A (0.56) MEN1KMT2ARAB9ANPC1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9383665-B2 Ammonium alkylphosphate containing intermediate transfer members XEROX CORPORATION (US) 2016-07-05 — — US disclosed
US-8906513-B2 Fuser member XEROX CORPORATION (US) 2014-12-09 — — US disclosed
US-8577267-B2 Transparent intermediate transfer members containing zinc oxide, polyarylsulfone, and polyetheramine XEROX CORPORATION (US) 2013-11-05 — — US disclosed
US-20130149639-A1 AMMONIUM ALKYLPHOSPHATE CONTAINING INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2013-06-13 — — US disclosed
US-8409719-B2 Ammonium alkylphosphate containing intermediate transfer members XEROX CORPORATION (US) 2013-04-02 — — US disclosed
US-8366969-B2 Phosphate ester polyamideimide mixture containing intermediate transfer members XEROX CORPORATION (US) 2013-02-05 — — US disclosed
US-20130009104-A1 AMMONIUM ALKYLPHOSPHATE CONTAINING INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2013-01-10 — — US disclosed
US-8329367-B2 Polyamideimide containing photoconductors XEROX CORPORATION (US) 2012-12-11 — — US disclosed
US-8252420-B2 Polyamideimide polybenzimidazole containing intermediate transfer members XEROX CORPORATION (US) 2012-08-28 — — US disclosed
US-20120183783-A1 POLYAMIDEIMIDE POLYBENZIMIDAZOLE CONTAINING INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2012-07-19 — — US disclosed
US-20120148816-A1 FUSER MEMBER XEROX CORPORATION (US) 2012-06-14 — — US disclosed
US-20120119160-A1 TRANSPARENT INTERMEDIATE TRANSFER MEMBERS CONTAINING ZINC OXIDE, POLYARYLSULFONE, AND POLYETHERAMINE XEROX CORPORATION (US) 2012-05-17 — — US disclosed
US-20120049122-A1 PHOSPHATE ESTER POLYAMIDEIMIDE MIXTURE CONTAINING INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2012-03-01 — — US disclosed
US-20110183245-A1 POLYAMIDEIMIDE CONTAINING PHOTOCONDUCTORS XEROX CORPORATION (US) 2011-07-28 — — US disclosed
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