Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | ST6GAL1 | P15907 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | GAPDH | P04406 | 2/20 | 0.43 |
| ▸ | HRAS | P01112 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16556343 | 1.00 | MEN1 (0.52) | MEN1USP2POLBKMT2AALDH1A1 | |
| SCHEMBL26647521 | 1.00 | MEN1 (0.52) | MEN1USP2POLBKMT2AALDH1A1 | |
| SCHEMBL6765430 | 0.91 | MEN1 (0.59) | MEN1USP2POLBKMT2AALDH1A1 | |
| SCHEMBL8516844 | 0.91 | MEN1 (0.59) | MEN1USP2POLBKMT2AALDH1A1 | |
| SCHEMBL14011209 | 0.91 | MEN1 (0.59) | MEN1USP2POLBKMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL11628090 | 0.90 | MEN1 (0.58) | MEN1USP2POLBKMT2AALDH1A1 | |
| SCHEMBL28197797 | 0.89 | LMNA (0.55) | MEN1USP2POLBKMT2AALDH1A1 | |
| SCHEMBL18271847 | 0.88 | MEN1 (0.54) | MEN1USP2POLBKMT2AALDH1A1 | |
| SCHEMBL16947995 | 0.88 | POLB (0.54) | MEN1USP2POLBKMT2AALDH1A1 | |
| SCHEMBL1525218 | 0.88 | ALDH1A1 (0.56) | ALDH1A1LMNATHRBMTORMDM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9481705-B2 | Modular radiochemistry synthesis system | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-11-01 | — | — | US | disclosed |
| US-20160130295-A1 | MODULAR RADIOCHEMISTRY SYNTHESIS SYSTEM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-05-12 | — | — | US | disclosed |
| US-20150329583-A1 | MODULAR RADIOCHEMISTRY SYNTHESIS SYSTEM | ENERGY, UNITED STATES DEPARTMENT OF | 2015-11-19 | — | — | US | disclosed |
| US-20120107175-A1 | MODULAR RADIOCHEMISTRY SYNTHESIS SYSTEM | THE REGENTS OF THE UNIVERISTY OF CALIFORNIA (US) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160130295-A1 | MODULAR RADIOCHEMISTRY SYNTHESIS SYSTEM | RAD18, MVD, USP18 | MEN1 669/4885USP2 538/4885POLB 416/4885 |
| US-20150329583-A1 | MODULAR RADIOCHEMISTRY SYNTHESIS SYSTEM | RAD18, MVD, USP18 | MEN1 669/4885USP2 538/4885POLB 416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.