Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 2/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12125350 | 0.79 | AURKA (0.34) | AURKA | |
| SCHEMBL12586215 | 0.77 | NUDT1 (0.35) | NUDT1AURKA | |
| SCHEMBL2516416 | 0.76 | NUDT1 (0.38) | NUDT1AURKA | |
| SCHEMBL12279163 | 0.69 | RAPGEF4 (0.45) | AURKA | |
| SCHEMBL18013747 | 0.69 | NUDT1 (0.41) | NUDT1 | |
| SCHEMBL12279562 | 0.68 | AURKA (0.54) | AURKA | |
| SCHEMBL859187 | 0.68 | EGFR (0.51) | AURKA | |
| SCHEMBL23472140 | 0.67 | TLR8 (0.44) | — | |
| SCHEMBL12279725 | 0.66 | STK17A (0.52) | AURKA | |
| SCHEMBL27631266 | 0.66 | TLR8 (0.43) | NUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9481705-B2 | Modular radiochemistry synthesis system | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-11-01 | — | — | US | disclosed |
| US-20160130295-A1 | MODULAR RADIOCHEMISTRY SYNTHESIS SYSTEM | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2016-05-12 | — | — | US | disclosed |
| US-9211520-B2 | Modular radiochemistry synthesis system | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-12-15 | — | — | US | disclosed |
| US-20150329583-A1 | MODULAR RADIOCHEMISTRY SYNTHESIS SYSTEM | ENERGY, UNITED STATES DEPARTMENT OF | 2015-11-19 | — | — | US | disclosed |
| US-8951480-B2 | Modular radiochemistry synthesis system | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-02-10 | — | — | US | disclosed |
| US-20120107175-A1 | MODULAR RADIOCHEMISTRY SYNTHESIS SYSTEM | THE REGENTS OF THE UNIVERISTY OF CALIFORNIA (US) | 2012-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160130295-A1 | MODULAR RADIOCHEMISTRY SYNTHESIS SYSTEM | RAD18, MVD, USP18 | NUDT1 1705/4885AURKA 726/4885 |
| US-20150329583-A1 | MODULAR RADIOCHEMISTRY SYNTHESIS SYSTEM | RAD18, MVD, USP18 | NUDT1 1705/4885AURKA 726/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.