SCHEMBL4570607

SCHEMBL4570607

Cc1ccc(COP=O)s1

nearest known ligand 0.44

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
PRMT6 Q96LA8 1/20 0.44
RIPK1 Q13546 1/20 0.38
THRB P10828 2/20 0.38
KDM4E B2RXH2 1/20 0.38
MEN1 O00255 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GAA P10253 1/20 0.38
MAPT P10636 1/20 0.38
HPGD P15428 1/20 0.38
KMT2A Q03164 1/20 0.38
HSD17B10 Q99714 1/20 0.38
TP53 P04637 1/20 0.37
TRPM8 Q7Z2W7 1/20 0.36
ADRA1D P25100 2/20 0.35
NPC1 O15118 1/20 0.35
RAB9A P51151 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
DAO P14920 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12461696 0.74
SCHEMBL19051432 0.72 PRMT6 (0.44) PRMT6RIPK1THRBKDM4EMEN1
SCHEMBL22733817 0.71 PRMT6 (0.47) PRMT6RIPK1THRBKDM4EMEN1
SCHEMBL13218002 0.71 PRMT6 (0.47) PRMT6RIPK1THRBKDM4EMEN1
SCHEMBL12508125 0.71 DPP4 (0.50) PRMT6RIPK1THRBKDM4EMEN1
SCHEMBL3035345 0.71 PRMT6 (0.42) PRMT6RIPK1THRBKDM4EMEN1
SCHEMBL10151101 0.69 PRMT6 (0.45) PRMT6RIPK1THRBKDM4EMEN1
SCHEMBL15493978 0.68 PRMT6 (0.40) PRMT6RIPK1THRBKDM4EMEN1
SCHEMBL14049755 0.68 PRMT6 (0.44) PRMT6RIPK1THRBKDM4EMEN1
SCHEMBL18355122 0.68 PRMT6 (0.44) PRMT6RIPK1THRBKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9133211-B2 Dithienobenzodithiophene semiconductive material and electronic device using the same RICOH COMPANY, LTD. (JP) 2015-09-15 US disclosed
US-20120119195-A1 NOVEL ORGANIC SEMICONDUCTIVE MATERIAL AND ELECTRONIC DEVICE USING THE SAME RICOH COMPANY, LTD. (JP) 2012-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120119195-A1 NOVEL ORGANIC SEMICONDUCTIVE MATERIAL AND ELECTRONIC DEVICE USING THE SAME RPS10, OR10J3, RPS20 PRMT6 900/4885RIPK1 3861/4885THRB 3859/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.