SCHEMBL4570683

SCHEMBL4570683

Cc1c2ccccc2c(C(=O)O)c2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.56
KMT2A Q03164 3/20 0.56
MEN1 O00255 2/20 0.56
HPGD P15428 2/20 0.56
ALDH1A1 P00352 1/20 0.56
CYP1A2 P05177 1/20 0.56
GLA P06280 1/20 0.56
CYP2C19 P33261 1/20 0.56
HSD17B10 Q99714 1/20 0.56
PDE10A Q9Y233 3/20 0.55
TSHR P16473 1/20 0.50
DHODH Q02127 4/20 0.47
LDHA P00338 1/20 0.44
LDHB P07195 1/20 0.44
PRNP P04156 1/20 0.43
RXFP1 Q9HBX9 1/20 0.43
EGFR P00533 1/20 0.43
TDP1 Q9NUW8 1/20 0.42
HTT P42858 1/20 0.42
MYC P01106 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL113091 0.88 PDE10A (0.62) KDM4EKMT2AMEN1HPGDALDH1A1
SCHEMBL655431 0.88 PDE10A (0.57) KDM4EKMT2AMEN1HPGDALDH1A1
Benzene SCHEMBL10558251 0.87 KDM4E (0.68) KDM4EKMT2AMEN1HPGDALDH1A1
SCHEMBL29599456 0.87 KDM4E (0.68) KDM4EKMT2AMEN1HPGDALDH1A1
SCHEMBL70004 0.87 KDM4E (0.68) KDM4EKMT2AMEN1HPGDALDH1A1
SCHEMBL31128390 0.86 PDE10A (0.52) KDM4EKMT2AMEN1HPGDALDH1A1
SCHEMBL497403 0.86 PDE10A (0.52) KDM4EKMT2AMEN1HPGDALDH1A1
SCHEMBL1905106 0.86 PDE10A (0.56) KDM4EKMT2AMEN1HPGDALDH1A1
SCHEMBL31436571 0.85 KDM4E (0.65) KDM4EKMT2AMEN1HPGDALDH1A1
Hydrochloric Acid SCHEMBL21173958 0.85 KDM4E (0.65) KDM4EKMT2AMEN1HPGDALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180197688-A1 PHOTOELECTRIC CONVERSION ELEMENT AND SOLAR CELL RICOH COMPANY, LTD. (JP) 2018-07-12 US disclosed
US-20160185968-A1 ORGANIC DYES HAVING RIGID DONOR, PROCESS FOR PRODUCING THE SAME, AND DYE-SENSITIZED SOLAR CELL CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2016-06-30 US disclosed
US-9376567-B1 Organic dyes having rigid donor, process for producing the same, and dye-sensitized solar cell CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) 2016-06-28 US disclosed
US-8940392-B2 Titanium based inorganic-organic hybrid solid material, method for preparing same and uses thereof UNIVERSITE PIERRE ET MARIE CURIE (PARIS 6) (FR) 2015-01-27 US disclosed
US-20120121904-A1 TITANIUM BASED INORGANIC-ORGANIC HYBRID SOLID MATERIAL, METHOD FOR PREPARING SAME AND USES THEREOF L'UNIVERSITE PIERRE ET MARIE CURIE, (PARIS 6) (FR) 2012-05-17 US disclosed
EP-0536208-B1 1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS RES CORP TECHNOLOGIES INC (US) 1998-01-21 EP disclosed
US-5635506-A ANTITUMOR AGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1997-06-03 US disclosed
EP-0660824-A1 1,2 DIHYDRO-3-H-DIBENZ(de,h) ISOQUINOLINE 1,3 DIONE AND THEIR USE AS ANTICANCER AGENTS RESEARCH CORPORATION TECHNOLOGIES (US) 1995-07-05 EP disclosed
WO-1994006771-A9 1,2 DIHYDRO-3-H-DIBENZ(de,h) ISOQUINOLINE 1,3 DIONE AND THEIR USE AS ANTICANCER AGENTS 1994-06-09 WO disclosed
WO-1994006771-A1 1,2 DIHYDRO-3-H-DIBENZ(de,h) ISOQUINOLINE 1,3 DIONE AND THEIR USE AS ANTICANCER AGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1994-03-31 WO disclosed
EP-0536208-A4 1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS 1993-05-05 EP disclosed
EP-0536208-A1 1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1993-04-14 EP disclosed
WO-1992000281-A1 1,2-DIHYDRO-3H-DIBENZISOQUINOLINE-1,3-DIONE ANTICANCER AGENTS RESEARCH CORPORATION TECHNOLOGIES, INC. (US) 1992-01-09 WO disclosed