SCHEMBL655431

SCHEMBL655431

Cc1c(C(=O)O)c(C(=O)O)c(C)c2ccccc12

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE10A Q9Y233 3/20 0.57
KMT2A Q03164 3/20 0.52
KDM4E B2RXH2 3/20 0.52
MEN1 O00255 2/20 0.52
ALDH1A1 P00352 2/20 0.52
CYP1A2 P05177 1/20 0.52
GLA P06280 1/20 0.52
HPGD P15428 1/20 0.52
CYP2C19 P33261 1/20 0.52
HSD17B10 Q99714 1/20 0.52
TSHR P16473 2/20 0.52
DHODH Q02127 4/20 0.49
HTT P42858 1/20 0.47
PRNP P04156 1/20 0.44
RXFP1 Q9HBX9 1/20 0.44
EGFR P00533 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
MYC P01106 1/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31128390 0.89 PDE10A (0.52) PDE10AKMT2AKDM4EMEN1ALDH1A1
SCHEMBL497403 0.89 PDE10A (0.52) PDE10AKMT2AKDM4EMEN1ALDH1A1
SCHEMBL4570683 0.88 KDM4E (0.56) PDE10AKMT2AKDM4EMEN1ALDH1A1
SCHEMBL973742 0.86 MEN1 (0.59) PDE10AKMT2AKDM4EMEN1ALDH1A1
SCHEMBL113091 0.85 PDE10A (0.62) PDE10AKMT2AKDM4EMEN1ALDH1A1
SCHEMBL6171244 0.85 PDE10A (0.49) PDE10AKMT2AKDM4EMEN1ALDH1A1
SCHEMBL27806469 0.85 PDE10A (0.49) PDE10AKMT2AKDM4EMEN1ALDH1A1
SCHEMBL5160775 0.85 PDE10A (0.49) PDE10AKMT2AKDM4EMEN1ALDH1A1
SCHEMBL1905106 0.84 PDE10A (0.56) PDE10AKMT2AKDM4EMEN1ALDH1A1
Cyclohexane SCHEMBL15141699 0.83 PDE10A (0.47) PDE10AKMT2AKDM4EMEN1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9018312-B2 Thermoplastic resin composition having improved impact resistance CHEIL INDUSTRIES INC. (KR) 2015-04-28 US claimed
US-7919559-B2 Chemical-resistant and impact-resistant thermoplastic resin composition with excellent hydrolysis resistance CHEIL INDUSTRIES INC. (KR) 2011-04-05 US claimed
EP-1515932-B1 METHOD FOR THE PRODUCTION OF 1,4- BUTANEDIOL BASF SE (DE) 2010-06-16 EP claimed
US-20100113673-A1 POLYMER NANOCOMPOSITES AND FABRICATION METHODS THEREOF INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2010-05-06 US claimed
US-20090137768-A1 RANDOM AMORPHOUS COPOLYMER AND MANUFACTURING METHOD THEREOF INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) 2009-05-28 US claimed
US-7271299-B2 Two-stage method for producing butanediol with intermediated separation of succinic anhydride BASF AKTIENGESELLSCHAFT (DE) 2007-09-18 US claimed
US-20060167323-A1 Two-stage method for producing butane diol with intermediated separation of succinic anhydride BASF AKTIENGESELLSCHAFT (DE) 2006-07-27 US claimed
EP-0335818-A2 Modified polyethylene naphthalate SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-10-04 EP claimed
US-4798883-A Modified polyethylene naphthalate THE GOODYEAR TIRE & RUBBER COMPANY (US) 1989-01-17 US claimed
US-20240059890-A1 Thermoplastic Resin Composition and Molded Product Manufactured Therefrom LOTTE CHEMICAL CORPORATION (KR) 2024-02-22 US disclosed
US-11732126-B2 Thermoplastic resin composition and molded product produced therefrom LOTTE CHEMICAL CORPORATION (KR) 2023-08-22 US disclosed
EP-4206281-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED ARTICLE FORMED THEREFROM Lotte Chemical Corporation (KR) 2023-07-05 EP disclosed
EP-4206284-A1 THERMOPLASTIC RESIN COMPOSITION AND MOLDED PRODUCT MANUFACTURED THEREFROM Lotte Chemical Corporation (KR) 2023-07-05 EP disclosed
US-11674036-B2 Thermoplastic polycarbonate resin composition including aromatic polyphosphonate and organic acid and article produced therefrom LOTTE CHEMICAL CORPORATION (KR) 2023-06-13 US disclosed
US-20060167323-A1 Two-stage method for producing butane diol with intermediated separation of succinic anhydride BASF AKTIENGESELLSCHAFT (DE) 2006-07-27 US disclosed
US-20050119494-A1 Method for the simultaneous production of tetrahydrofurans ad pyrrolidones BASF AKTIENGESELLSCHAFT (DE) 2005-06-02 US disclosed
EP-1073620-B1 METHOD FOR PRODUCING 1,4-BUTANEDIOL BASF AG (DE) 2003-07-09 EP disclosed
EP-1073620-A1 METHOD FOR PRODUCING 1,4-BUTANEDIOL BASF AKTIENGESELLSCHAFT (DE) 2001-02-07 EP disclosed
WO-1999055659-A1 METHOD FOR PRODUCING 1,4-BUTANEDIOL BASF AKTIENGESELLSCHAFT (DE) 1999-11-04 WO disclosed
US-5294695-A Catalytic polymerization of a dialkanol ester at high pressure and controlling the viscosity SKC LIMITED (KR) 1994-03-15 US disclosed