Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | FOLH1 | Q04609 | 4/20 | 0.44 |
| ▸ | FOLR1 | P15328 | 6/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | PGR | P06401 | 1/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12971804 | 1.00 | PTPN1 (0.50) | PTPN1HTR1AFOLH1FOLR1CHRM1 | |
| SCHEMBL16503334 | 0.97 | PTPN1 (0.46) | PTPN1HTR1AFOLH1FOLR1CHRM1 | |
| SCHEMBL12971922 | 0.97 | PTPN1 (0.47) | PTPN1HTR1AFOLH1FOLR1CHRM1 | |
| SCHEMBL12971809 | 0.94 | PTPN1 (0.48) | PTPN1HTR1AFOLH1FOLR1CHRM1 | |
| SCHEMBL18263260 | 0.92 | PTPN1 (0.57) | PTPN1HTR1AFOLH1FOLR1CHRM1 | |
| SCHEMBL18263258 | 0.92 | PTPN1 (0.57) | PTPN1HTR1AFOLH1FOLR1CHRM1 | |
| SCHEMBL15095695 | 0.92 | PTPN1 (0.57) | PTPN1HTR1AFOLH1FOLR1CHRM1 | |
| Water SCHEMBL30750796 | 0.91 | PTPN1 (0.57) | PTPN1HTR1AFOLH1FOLR1CHRM1 | |
| Water SCHEMBL17099468 | 0.91 | PTPN1 (0.57) | PTPN1HTR1AFOLH1FOLR1CHRM1 | |
| Water SCHEMBL17099467 | 0.91 | PTPN1 (0.57) | PTPN1HTR1AFOLH1FOLR1CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8168804-B2 | Large stoke shift NIR dyes | VANDERBILT UNIVERSITY (US) | 2012-05-01 | — | — | US | disclosed |
| US-20090029405-A1 | LARGE STOKE SHIFT NIR DYES | VANDERBILT UNIVERSITY | 2009-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090029405-A1 | LARGE STOKE SHIFT NIR DYES | SLC7A5, SLC43A1, SPIN3 | PTPN1 4518/4885HTR1A 2696/4885FOLH1 531/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.