Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G4A | P47712 | 20/20 | 0.71 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13127474 | 0.91 | PLA2G4A (0.57) | PLA2G4A | |
| SCHEMBL2807000 | 0.90 | PLA2G4A (0.58) | PLA2G4A | |
| SCHEMBL459459 | 0.86 | PLA2G4A (0.61) | PLA2G4A | |
| SCHEMBL2807002 | 0.83 | PLA2G4A (0.59) | PLA2G4A | |
| SCHEMBL3930485 | 0.82 | PLA2G4A (1.00) | PLA2G4A | |
| SCHEMBL3924439 | 0.80 | PLA2G4A (1.00) | PLA2G4A | |
| SCHEMBL6151988 | 0.80 | PLA2G4A (0.85) | PLA2G4A | |
| SCHEMBL3930564 | 0.80 | PLA2G4A (1.00) | PLA2G4A | |
| SCHEMBL3933291 | 0.80 | PLA2G4A (1.00) | PLA2G4A | |
| SCHEMBL2807398 | 0.80 | PLA2G4A (0.88) | PLA2G4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2614144-B1 | USE OF INHIBITORS OF PHOSPHOLIPASE A2 FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTION | TWINCORE ZENTRUM FÜR EXPERIMENTELLE UND KLINISCHE INFEKTIONSFORSCHUNG GMBH (DE) | 2015-07-22 | — | — | EP | claimed |
| US-20130209403-A1 | USE OF INHIBITORS OF PHOSPHOLIPASE A2 FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTION | RUPRECHT-KARLS-UNIVERSITAET (DE) | 2013-08-15 | — | — | US | claimed |
| EP-2614144-B1 | USE OF INHIBITORS OF PHOSPHOLIPASE A2 FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTION | TWINCORE ZENTRUM FÜR EXPERIMENTELLE UND KLINISCHE INFEKTIONSFORSCHUNG GMBH (DE) | 2015-07-22 | — | — | EP | disclosed |
| US-20130209403-A1 | USE OF INHIBITORS OF PHOSPHOLIPASE A2 FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTION | RUPRECHT-KARLS-UNIVERSITAET (DE) | 2013-08-15 | — | — | US | disclosed |
| EP-2614144-A1 | USE OF INHIBITORS OF PHOSPHOLIPASE A2 FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTION | Twincore Zentrum für Experimentelle und Klinische Infektionsforschung GmbH (DE) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012031763-A1 | USE OF INHIBITORS OF PHOSPHOLIPASE A2 FOR THE TREATMENT OR PREVENTION OF FLAVIVIRUS INFECTION | TWINCORE ZENTRUM FUER EXPERIMENTELLE UND KLINISCHE INFEKTIONSFORSCHUNG GMBH (DE) | 2012-03-15 | — | — | WO | disclosed |
| US-20100240718-A1 | NOVEL HETEROARYL-SUBSTITUTED ACETONE DERIVATIVE, SUITABLE FOR INHIBITING PHOSPHOLIPASE A2 | WESTFALISCHE WILHELMS UNIVERSITÄT MÜNSTER (DE) | 2010-09-23 | — | — | US | disclosed |
| WO-2009040314-A2 | NOVEL HETEROARYL-SUBSTITUTED ACETONE DERIVATIVES, SUITABLE FOR INHIBITING PHOSPHOLIPASE A2 | Westfälische Wilhelms Universität Münster (DE) | 2009-04-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240718-A1 | NOVEL HETEROARYL-SUBSTITUTED ACETONE DERIVATIVE, SUITABLE FOR INHIBITING PHOSPHOLIPASE A2 | PLD2, PLA2G1B, PLA2G4A | PLA2G4A 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.