Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 1/20 | 0.56 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KMO | O15229 | 1/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.47 |
| ▸ | ACLY | P53396 | 4/20 | 0.47 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4302847 | 0.89 | DYRK1A (0.65) | DYRK1ACHEK1L3MBTL1MEN1KMT2A | |
| SCHEMBL29148445 | 0.86 | DYRK1A (0.57) | DYRK1ACHEK1L3MBTL1KMOEGLN2 | |
| Chloroneb SCHEMBL4292226 | 0.85 | MAPK10 (0.51) | L3MBTL1MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL29375895 | 0.84 | ADORA2A (0.55) | L3MBTL1MEN1KMT2AKMOESR2 | |
| SCHEMBL403698 | 0.84 | ADORA2A (0.55) | L3MBTL1MEN1KMT2AKMOESR2 | |
| SCHEMBL21586174 | 0.83 | DYRK1A (0.51) | DYRK1ACHEK1EGLN2CYP3A4 | |
| SCHEMBL21084582 | 0.82 | DYRK1A (0.63) | DYRK1ACHEK1KMOEGLN2ALDH1A1 | |
| SCHEMBL4533772 | 0.81 | L3MBTL1 (0.62) | L3MBTL1MEN1KMT2AALDH1A1TSHR | |
| SCHEMBL21289787 | 0.80 | L3MBTL1 (0.75) | L3MBTL1MEN1KMT2AALDH1A1TDP1 | |
| SCHEMBL12945558 | 0.78 | CHEK1 (0.49) | DYRK1ACHEK1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110394190-B | Nitrogen-rich triazine-based calix [4] arene polymer supported palladium catalyst, and preparation method and application thereof | 上海应用技术大学 | 2022-04-01 | — | — | CN | disclosed |
| EP-2614053-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012033225-A1 | METHOD FOR PRODUCING PYRIDAZINONE COMPOUNDS AND INTERMEDIATE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-03-15 | — | — | WO | disclosed |