SCHEMBL4533772

SCHEMBL4533772

COc1ccc(-c2ccccc2)cc1OC

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.62
NPC1 O15118 2/20 0.62
RAB9A P51151 2/20 0.62
KMT2A Q03164 4/20 0.61
KDM4E B2RXH2 4/20 0.61
ALDH1A1 P00352 4/20 0.61
MEN1 O00255 3/20 0.61
HPGD P15428 2/20 0.61
HSD17B10 Q99714 2/20 0.61
USP2 O75604 1/20 0.61
TSHR P16473 1/20 0.61
MAPK1 P28482 1/20 0.61
HTT P42858 1/20 0.61
ATM Q13315 1/20 0.61
LMNA P02545 1/20 0.58
MAPT P10636 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
ACACA Q13085 1/20 0.56
PDE4A P27815 1/20 0.55
AGTR1 P30556 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetaldehyde SCHEMBL27798693 0.90 L3MBTL1 (0.54) L3MBTL1NPC1RAB9AKMT2AKDM4E
SCHEMBL434623 0.89 L3MBTL1 (0.53) L3MBTL1NPC1RAB9AKMT2AKDM4E
SCHEMBL21247766 0.89 L3MBTL1 (0.53) L3MBTL1NPC1RAB9AKMT2AKDM4E
SCHEMBL16541896 0.88 PDE4A (0.57) L3MBTL1NPC1RAB9AKMT2AKDM4E
SCHEMBL8840880 0.88 PDE4A (0.67) L3MBTL1NPC1RAB9AKMT2AKDM4E
SCHEMBL30196055 0.85 MAPT (0.54) L3MBTL1NPC1RAB9AKMT2AKDM4E
SCHEMBL30196061 0.85 KDM4E (0.52) L3MBTL1NPC1RAB9AKMT2AKDM4E
SCHEMBL29137690 0.85 L3MBTL1 (0.49) L3MBTL1NPC1RAB9AKMT2AKDM4E
SCHEMBL31495215 0.85 L3MBTL1 (0.49) L3MBTL1NPC1RAB9AKMT2AKDM4E
SCHEMBL8678736 0.83 PDE4A (0.50) L3MBTL1NPC1RAB9AKMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102911619-A Assistant composite activated by ultraviolet light and adhesive containing composite GUANGDONG HENGDA NEW MATERIALS TECHNOLOGY CO LTD 2013-02-06 CN claimed
CN-101068773-A Melanin concentrating hormone antagonists PROCTER & GAMBLE (US) 2007-11-07 CN claimed
EP-1667958-A2 MELANIN CONCENTRATING HORMONE ANTAGONISTS THE PROCTER & GAMBLE COMPANY (US) 2006-06-14 EP claimed
WO-2005033063-A2 MELANIN CONCENTRATING HORMONE ANTAGONISTS THE PROCTER & GAMBLE COMPANY (US) 2005-04-14 WO claimed
US-20050075324-A1 Melanin concentrating hormone antagonists THE PROCTER & GAMBLE COMPANY (US) 2005-04-07 US claimed
EP-3805192-B1 NOVEL BIPHENYL DERIVATIVE COMPOUND AND USE THEREOF UNIV EWHA IND COLLABORATION (KR) 2024-09-11 EP disclosed
CN-118598725-A Method for preparing biaryl compound by palladium-catalyzed desulfonyl chloride removal 平湖石化有限责任公司 2024-09-06 CN disclosed
CN-117024352-A Novel inhibitors 维沃里翁治疗股份有限公司 2023-11-10 CN disclosed
CN-112513000-B Novel biphenyl derivative compound and use thereof 梨花女子大学校产学协力团 2023-09-08 CN disclosed
CN-110719910-B Novel inhibitors 维沃里翁治疗股份有限公司 2023-07-21 CN disclosed
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes Ambient Photonics, Inc. (US) 2023-05-30 US disclosed
US-20230047816-A1 PFKFB3 INHIBITORS AND THEIR USES GERO PTE. LTD. (SG) 2023-02-16 US disclosed
US-7304065-B2 Melanin concentrating hormone antagonists THE PROCTER & GAMBLE COMPANY (US) 2007-12-04 US disclosed
CN-101068773-A Melanin concentrating hormone antagonists PROCTER & GAMBLE (US) 2007-11-07 CN disclosed
US-7223879-B2 Ligands for metals and improved metal-catalyzed processes based thereon MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2007-05-29 US disclosed
US-20060247239-A1 Melanin concentrating hormone antagonists HU XIUFENG E 2006-11-02 US disclosed
EP-1667958-A2 MELANIN CONCENTRATING HORMONE ANTAGONISTS THE PROCTER & GAMBLE COMPANY (US) 2006-06-14 EP disclosed
US-6927216-B2 Cyclic sulfonyl compounds as inhibitors of metalloproteases BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) 2005-08-09 US disclosed
WO-2005033063-A2 MELANIN CONCENTRATING HORMONE ANTAGONISTS THE PROCTER & GAMBLE COMPANY (US) 2005-04-14 WO disclosed
US-20050075324-A1 Melanin concentrating hormone antagonists THE PROCTER & GAMBLE COMPANY (US) 2005-04-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230047816-A1 PFKFB3 INHIBITORS AND THEIR USES PFKFB3, PFKFB4, PFKFB1 L3MBTL1 4205/4885NPC1 4357/4885RAB9A 4602/4885
US-20050075324-A1 Melanin concentrating hormone antagonists MCHR1, MCHR2, MC1R L3MBTL1 2186/4885NPC1 1263/4885RAB9A 2216/4885
US-20060247239-A1 Melanin concentrating hormone antagonists MCHR1, MCHR2, MC1R L3MBTL1 2186/4885NPC1 1263/4885RAB9A 2216/4885
US-11664171-B2 Stilbene and fused stilbene derivatives as solar cell dyes SUN2, FDFT1, SIK1 L3MBTL1 4577/4885NPC1 3043/4885RAB9A 3248/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.