Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.46 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.43 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.43 |
| ▸ | MPO | P05164 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 2/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4568120 | 0.88 | RAB9A (0.47) | LOXL2RAB9ACYP4F2CYP4A11MPO | |
| SCHEMBL4568118 | 0.88 | RAB9A (0.47) | LOXL2RAB9ACYP4F2CYP4A11MPO | |
| SCHEMBL4568122 | 0.87 | MRGPRX4 (0.47) | LOXL2RAB9ACYP4F2CYP4A11KIF11 | |
| SCHEMBL4568107 | 0.87 | RAB9A (0.46) | LOXL2RAB9ACYP4F2CYP4A11KIF11 | |
| SCHEMBL4568110 | 0.87 | RAB9A (0.49) | LOXL2RAB9ACYP4F2CYP4A11KIF11 | |
| SCHEMBL4568123 | 0.85 | MRGPRX4 (0.49) | LOXL2RAB9ACYP4F2CYP4A11KIF11 | |
| SCHEMBL10314414 | 0.83 | MDM4 (0.46) | LOXL2RAB9ACYP4F2CYP4A11MPO | |
| SCHEMBL4568146 | 0.77 | MRGPRX4 (0.49) | RAB9ANPC1SMN1; SMN2MRGPRX4 | |
| SCHEMBL4568165 | 0.77 | GPR17 (0.43) | KIF11DHFRSMN1; SMN2MRGPRX4 | |
| SCHEMBL4568168 | 0.76 | MRGPRX4 (0.48) | KIF11MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120122931-A1 | INDOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2012-05-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120122931-A1 | INDOLE DERIVATIVE OR PHARMACEUTICALLY ACCEPTABLE SALT THEREOF | PTGER1, CYSLTR1, LTB4R | LOXL2 405/4885RAB9A 1646/4885CYP4F2 2963/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.