SCHEMBL4572155

SCHEMBL4572155

CCc1ccc(COc2ccc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)cc2)c(OC(C)CC(=O)OC)c1

nearest known ligand 0.32

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 4/20 0.32
KCNH2 Q12809 1/20 0.32
MCHR1 Q99705 1/20 0.32
FFAR4 Q5NUL3 2/20 0.32
S1PR1 P21453 2/20 0.31
PPARG P37231 2/20 0.30
DHODH Q02127 1/20 0.30
NR3C1 P04150 1/20 0.30
HPGD P15428 1/20 0.30
PPARD Q03181 1/20 0.30
PPARA Q07869 1/20 0.30
MME P08473 1/20 0.30
ACE P12821 1/20 0.30
CPA1 P15085 1/20 0.30
ACE2 Q9BYF1 1/20 0.30
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL39056 0.89 POLB (0.37) FFAR1KCNH2MCHR1FFAR4S1PR1
SCHEMBL21300527 0.89 POLB (0.37) FFAR1KCNH2MCHR1FFAR4S1PR1
SCHEMBL4829878 0.87 PPARG (0.40) FFAR1FFAR4PPARGPPARDPPARA
SCHEMBL4829867 0.87 PPARG (0.40) FFAR1FFAR4PPARGPPARDPPARA
SCHEMBL5467634 0.86 L3MBTL1 (0.39) FFAR1FFAR4S1PR1PPARGHPGD
SCHEMBL7760397 0.85 PPARG (0.33) FFAR1FFAR4S1PR1PPARGPPARA
SCHEMBL7760390 0.81 PPARD (0.43) PPARGPPARDPPARA
Bromoxynil SCHEMBL7585447 0.80 POLB (0.31)
Clopyralid SCHEMBL7580470 0.80 PPARG (0.35) PPARGPPARDPPARA
Diclofop-Methyl SCHEMBL7587664 0.80 FFAR1 (0.34) FFAR1PPARGHPGDHTR2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8293979-B2 Weed controller metabolism proteins, genes, thereof and use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2012-10-23 US disclosed
EP-2453018-A1 A herbicide metabolizing protein, a gene thereof and use thereof Sumitomo Chemical Company, Limited (JP) 2012-05-16 EP disclosed
US-20100313300-A1 WEED CONTROLLER METABOLISM PROTEINS, GENES, THEREOF AND USE OF THE SAME SUMITOMO CHEMICAL COMPANY, LIMITED 2010-12-09 US disclosed
US-7745699-B2 Weed controller metabolism proteins, genes thereof and use of the same SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2010-06-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100313300-A1 WEED CONTROLLER METABOLISM PROTEINS, GENES, THEREOF AND USE OF THE SAME HADHB, WEE1, AS3MT FFAR1 3213/4885KCNH2 4472/4885MCHR1 2798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.