Clopyralid

Clopyralid

SCHEMBL7580470

CCc1ccc(COc2ccc(-n3c(=O)cc(C(F)(F)F)n(C)c3=O)cc2)c(OC(C)C(=O)OC)c1.O=C(O)c1nc(Cl)ccc1Cl

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PPARG P37231 11/20 0.35
L3MBTL1 Q9Y468 2/20 0.34
MEN1 O00255 1/20 0.34
MAPT P10636 1/20 0.34
KMT2A Q03164 1/20 0.34
POLB P06746 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
PTGDR2 Q9Y5Y4 2/20 0.31
PPARD Q03181 1/20 0.31
PPARA Q07869 1/20 0.31
P2RX3 P56373 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21300527 0.90 POLB (0.37) PPARGL3MBTL1POLBSMN1; SMN2
SCHEMBL39056 0.90 POLB (0.37) PPARGL3MBTL1POLBSMN1; SMN2
Pyrithiobac SCHEMBL7580364 0.85 PPARG (0.31) PPARG
Diclofop-Methyl SCHEMBL7587664 0.85 FFAR1 (0.34) PPARGL3MBTL1POLBSMN1; SMN2P2RX3
SCHEMBL5467634 0.84 L3MBTL1 (0.39) PPARGL3MBTL1MAPTPOLBSMN1; SMN2
SCHEMBL4829878 0.84 PPARG (0.40) PPARGPPARDPPARA
SCHEMBL4829867 0.84 PPARG (0.40) PPARGPPARDPPARA
Terbuthylazine SCHEMBL7580710 0.84 GAA (0.33) PPARGPOLBSMN1; SMN2
Bispyribac SCHEMBL7577860 0.83 POLB (0.32) PPARGPOLBSMN1; SMN2
Pyrazon SCHEMBL7581362 0.83 ALDH1A1 (0.32) L3MBTL1MAPTKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020004457-A1 Herbicidal composition SYNGENTA PARTICIPATIONS AG (CH) 2002-01-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020004457-A1 Herbicidal composition PPOX, ALAD, DDT PPARG 777/4885L3MBTL1 2160/4885MEN1 4274/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.