SCHEMBL457225

SCHEMBL457225

Fc1ccc(N=C=S)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MIF P14174 2/20 0.56
P2RY6 Q15077 3/20 0.56
CA1 P00915 2/20 0.48
CA2 P00918 2/20 0.48
HSD17B10 Q99714 3/20 0.41
SLC22A2 O15244 1/20 0.41
SLC22A1 O15245 1/20 0.41
SLC22A3 O75751 1/20 0.41
PLAU P00749 1/20 0.41
NOS3 P29474 2/20 0.39
NOS1 P29475 2/20 0.39
PNMT P11086 1/20 0.36
KDM4E B2RXH2 2/20 0.35
USP2 O75604 2/20 0.35
ALDH1A1 P00352 2/20 0.35
LTA P01374 2/20 0.35
CYP3A4 P08684 2/20 0.35
MAPT P10636 2/20 0.35
HPGD P15428 2/20 0.35
P2RX3 P56373 2/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5411760 0.89 P2RY6 (0.47) MIFP2RY6CA1CA2HSD17B10
Bitoscanate SCHEMBL157128 0.86 MIF (0.72) MIFP2RY6CA1CA2HSD17B10
SCHEMBL20184801 0.78 SLC22A2 (0.44) MIFP2RY6CA1CA2SLC22A2
SCHEMBL1548531 0.78 MIF (0.62) MIFP2RY6CA1CA2HSD17B10
SCHEMBL8506851 0.77 P2RY6 (0.40) MIFP2RY6CA1CA2HSD17B10
SCHEMBL14344845 0.76 MIF (0.59) MIFP2RY6CA1CA2HSD17B10
SCHEMBL25305038 0.74 SLC22A2 (0.41) MIFP2RY6CA1CA2SLC22A2
SCHEMBL331404 0.74 MIF (0.56) MIFP2RY6CA1CA2HSD17B10
SCHEMBL449738 0.74 MIF (0.56) MIFP2RY6CA1CA2HSD17B10
SCHEMBL13881813 0.74 MIF (0.56) MIFP2RY6CA1CA2HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 859 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12402638-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2025-09-02 US claimed
CN-115515998-B Synthesis of polyurethanes by chain growth copolymerization 伊夫·雅努 2025-06-24 CN claimed
US-20250194617-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-06-19 US claimed
CN-116947780-B Preparation method of thiazolidine-4-thioketone derivative 华侨大学 2025-06-03 CN claimed
US-20250169514-A1 Materials and Methods for Extending Shelf-Life of Foods JP LABORATORIES, INC. 2025-05-29 US claimed
US-12232516-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2025-02-25 US claimed
US-12193465-B2 Materials and methods for extending shelf-life of foods JP LABORATORIES, INC. (US) 2025-01-14 US claimed
CN-119080660-A Thiosemicarbazide menthyl formate compound, preparation method and application thereof 南京林业大学 2024-12-06 CN claimed
CN-118738556-A Electrolyte and lithium metal battery 蜂巢能源科技股份有限公司 2024-10-01 CN claimed
CN-117924210-A Preparation method of 2-iminothiazolidine-4-ketone compound 赣南师范大学 2024-04-26 CN claimed
CN-105267967-A Combined application of isothiocyanate-type compound and anti-cancer drug acting or affecting DNA WUXI JC PHARMACAUTICAL TECHNOLOGY INC 2016-01-27 CN claimed
CN-104415332-A Combined application between isothiocyanate-type compound and kinase inhibitor medicine in treatment of cancer WUXI JC PHARMACAUTICAL TECHNOLOGY INC 2015-03-18 CN claimed
US-8940434-B2 Electrolyte additive and electrolyte and lithium rechargeable battery including same SAMSUNG SDI CO., LTD. (KR) 2015-01-27 US claimed
CN-104117064-A Combined application of isothiocyanate compound and hormone medicine WUXI JC PHARMACAUTICAL TECHNOLOGY INC 2014-10-29 CN claimed
CN-103992265-A Double tribromo 1,3-bipyridine onium salt dimethylmethane, and preparation method, application method, recovery method and application thereof UNIV XI AN JIAOTONG 2014-08-20 CN claimed
CN-103864655-A Synthetic method of dehydroabietic acid group thiourea derivative UNIV GUANGXI 2014-06-18 CN claimed
US-20140134480-A1 ELECTROLYTE ADDITIVE AND ELECTROLYTE AND LITHIUM RECHARGEABLE BATTERY INCLUDING SAME SAMSUNG SDI CO., LTD. (KR) 2014-05-15 US claimed
WO-2010065329-A2 NANOPARTICLES FOR CANCER TREATMENT THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2010-06-10 WO claimed
US-20060241178-A1 Compositions and methods for treating lung cancer IMMUNEGUARD LLC (US) 2006-10-26 US claimed
WO-2004060365-A1 COMPOSITIONS AND METHODS FOR TREATING LUNG CANCER AMERICAN HEALTH FOUNDATION (US) 2004-07-22 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140134480-A1 ELECTROLYTE ADDITIVE AND ELECTROLYTE AND LITHIUM RECHARGEABLE BATTERY INCLUDING SAME TST, SLC26A3, CLCN2 MIF 3547/4885P2RY6 3427/4885CA1 391/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.