Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.67 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.64 |
| ▸ | CDK1 | P06493 | 2/20 | 0.64 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.64 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.53 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.53 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.53 |
| ▸ | MITF | O75030 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.52 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.52 |
| ▸ | TMIGD3 | P0DMS9 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15167412 | 0.92 | HTT (0.63) | HTTCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL457947 | 0.88 | HTT (0.70) | HTTCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL20119633 | 0.88 | HTT (0.67) | HTTCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL15167431 | 0.86 | HTT (0.67) | HTTCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL20097160 | 0.86 | CCNB2 (0.69) | HTTCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL31711723 | 0.84 | HTT (0.61) | HTTCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL31711717 | 0.84 | HTT (0.61) | HTTCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL20119629 | 0.83 | CDK1 (0.72) | HTTCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL31711716 | 0.83 | HTT (0.60) | HTTCCNB2CDK1CCNB1CCNB3 | |
| SCHEMBL31711719 | 0.83 | HTT (0.60) | HTTCCNB2CDK1CCNB1CCNB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2613631-B1 | USE OF 6-SUBSTITUTED 9-HALOGENALKYL PURINES FOR REGULATION OF GROWTH AND DEVELOPMENT OF WHOLE PLANTS, PLANT CELLS AND PLANT ORGANS; NOVEL 6-SUBSTITUTED 9-HALOGENALKYL PURINES | Univerzita Palackého v Olomouci (CZ) | 2016-04-13 | — | — | EP | disclosed |
| US-9220269-B2 | Use of 6-substituted 9-halogenalkyl purines for regulation of growth and development of whole plants, plant cells and plant organs; novel 6-substituted 9-halogenalkyl purines | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2015-12-29 | — | — | US | disclosed |
| US-20130210632-A1 | USE OF 6- SUBSTITUTED 9 - HALOGENALKYL PURINES FOR REGULATION OF GROWTH AND DEVELOPMENT OF WHOLE PLANTS, PLANT CELLS AND PLANT ORGANS; NOVEL 6 - SUBSTITUTED 9 - HALOGENALKYL PURINES | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2013-08-15 | — | — | US | disclosed |
| EP-2613631-A1 | USE OF 6 - SUBSTITUTED 9 - HALOGENALKYL PURINES FOR REGULATION OF GROWTH AND DEVELOPMENT OF WHOLE PLANTS, PLANT CELLS AND PLANT ORGANS; NOVEL 6 - SUBSTITUTED 9 -HALOGENALKYL PURINES | Univerzita Palackého v Olomouci (CZ) | 2013-07-17 | — | — | EP | disclosed |
| WO-2012031574-A1 | USE OF 6 - SUBSTITUTED 9 - HALOGENALKYL PURINES FOR REGULATION OF GROWTH AND DEVELOPMENT OF WHOLE PLANTS, PLANT CELLS AND PLANT ORGANS; NOVEL 6 - SUBSTITUTED 9 -HALOGENALKYL PURINES | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2012-03-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130210632-A1 | USE OF 6- SUBSTITUTED 9 - HALOGENALKYL PURINES FOR REGULATION OF GROWTH AND DEVELOPMENT OF WHOLE PLANTS, PLANT CELLS AND PLANT ORGANS; NOVEL 6 - SUBSTITUTED 9 - HALOGENALKYL PURINES | PURB, METTL3, UMPS | HTT 3228/4885CCNB2 1143/4885CDK1 1502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.