SCHEMBL4572500

SCHEMBL4572500

O=c1c2ccccc2oc2cc(-c3cccc(-c4ccc5c(=O)c6ccccc6oc5c4)c3)ccc12

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.64
KDM4E B2RXH2 2/20 0.64
ALDH1A1 P00352 2/20 0.64
CYP3A4 P08684 2/20 0.64
MAPT P10636 2/20 0.64
HPGD P15428 2/20 0.64
HSD17B10 Q99714 2/20 0.64
GLA P06280 1/20 0.64
PGAM1 P18669 1/20 0.64
CASP1 P29466 1/20 0.64
CASP7 P55210 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.64
HCRTR1 O43613 1/20 0.62
NPC1 O15118 4/20 0.57
RAB9A P51151 4/20 0.57
TTR P02766 2/20 0.57
ATM Q13315 1/20 0.56
PLA2G2A P14555 2/20 0.55
PLA2G4A P47712 2/20 0.55
MEN1 O00255 3/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4572524 1.00 MAOA (0.64) MAOAKDM4EALDH1A1CYP3A4MAPT
SCHEMBL4572506 1.00 MAOA (0.64) MAOAKDM4EALDH1A1CYP3A4MAPT
SCHEMBL12181795 0.95 MAOA (0.58) MAOAKDM4EALDH1A1CYP3A4MAPT
SCHEMBL4572518 0.95 MAOA (0.58) MAOAKDM4EALDH1A1CYP3A4MAPT
SCHEMBL4572514 0.95 MAOA (0.58) MAOAKDM4EALDH1A1CYP3A4MAPT
SCHEMBL10610131 0.93 MAOA (0.64) MAOAKDM4EALDH1A1CYP3A4MAPT
SCHEMBL4572440 0.92 PLA2G2A (0.56) MAOAKDM4EALDH1A1CYP3A4MAPT
SCHEMBL22649917 0.89 HCRTR1 (0.56) MAOAKDM4EALDH1A1CYP3A4MAPT
SCHEMBL22650027 0.89 HCRTR1 (0.56) MAOAKDM4EALDH1A1CYP3A4MAPT
SCHEMBL4572503 0.89 MAOA (0.64) MAOAKDM4EALDH1A1CYP3A4MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2635561-B1 XANTHONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KK (JP) 2016-12-14 EP disclosed
US-9318712-B2 Xanthone compound and organic light-emitting device including the same CANON KABUSHIKI KAISHA (JP) 2016-04-19 US disclosed
US-9318712-B2 Xanthone compound and organic light-emitting device including the same CANON KABUSHIKI KAISHA (JP) 2016-04-19 US disclosed
US-20130214268-A1 XANTHONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-22 US disclosed
US-20130214268-A1 XANTHONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-22 US disclosed
WO-2012060234-A1 XANTHONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-05-10 WO disclosed