SCHEMBL4572502

SCHEMBL4572502

O=c1c2ccccc2oc2ccc(-c3ccc(-c4ccc5oc6ccccc6c(=O)c5c4)cc3)cc12

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 5/20 0.69
MAPT P10636 2/20 0.69
SMN1; SMN2 Q16637 2/20 0.69
KDM4E B2RXH2 1/20 0.69
ALDH1A1 P00352 1/20 0.69
GLA P06280 1/20 0.69
CYP3A4 P08684 1/20 0.69
HPGD P15428 1/20 0.69
PGAM1 P18669 1/20 0.69
CASP1 P29466 1/20 0.69
CASP7 P55210 1/20 0.69
HSD17B10 Q99714 1/20 0.69
CASP3 P42574 1/20 0.66
SENP7 Q9BQF6 1/20 0.66
SENP6 Q9GZR1 1/20 0.66
TTR P02766 2/20 0.60
NPC1 O15118 6/20 0.58
RAB9A P51151 5/20 0.58
POLB P06746 1/20 0.58
L3MBTL1 Q9Y468 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12608739 0.98 MAOA (0.72) MAOAMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL6897957 0.96 MAOA (0.64) MAOAMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL4572490 0.96 MAOA (0.69) MAOAMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL4572517 0.95 MAOA (0.62) MAOAMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL4572523 0.95 MAOA (0.62) MAOAMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL4572526 0.93 PLA2G2A (0.60) MAOAMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL12181788 0.93 PLA2G2A (0.60) MAOAMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL4572507 0.93 MAOA (0.60) MAOAMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL4572444 0.93 MAOA (0.60) MAOAMAPTSMN1; SMN2KDM4EALDH1A1
SCHEMBL4572515 0.93 PLA2G2A (0.60) MAOAMAPTSMN1; SMN2KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2635561-B1 XANTHONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KK (JP) 2016-12-14 EP disclosed
US-9318712-B2 Xanthone compound and organic light-emitting device including the same CANON KABUSHIKI KAISHA (JP) 2016-04-19 US disclosed
US-9318712-B2 Xanthone compound and organic light-emitting device including the same CANON KABUSHIKI KAISHA (JP) 2016-04-19 US disclosed
US-20130214268-A1 XANTHONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-22 US disclosed
US-20130214268-A1 XANTHONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2013-08-22 US disclosed
WO-2012060234-A1 XANTHONE COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CANON KABUSHIKI KAISHA (JP) 2012-05-10 WO disclosed