Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 20/20 | 0.59 |
| ▸ | NTRK1 | P04629 | 3/20 | 0.49 |
| ▸ | KIT | P10721 | 3/20 | 0.49 |
| ▸ | SRC | P12931 | 3/20 | 0.49 |
| ▸ | FLT3 | P36888 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4763078 | 0.89 | CSF1R (0.58) | CSF1RNTRK1KITSRCFLT3 | |
| SCHEMBL4777730 | 0.85 | CSF1R (0.57) | CSF1RNTRK1KITSRCFLT3 | |
| SCHEMBL4771164 | 0.83 | CSF1R (0.63) | CSF1RNTRK1KITSRCFLT3 | |
| SCHEMBL4573708 | 0.83 | CSF1R (0.50) | CSF1RNTRK1KITSRCFLT3 | |
| SCHEMBL4594732 | 0.81 | CSF1R (0.66) | CSF1RNTRK1KITSRCFLT3 | |
| SCHEMBL4572926 | 0.80 | CSF1R (0.53) | CSF1RNTRK1KITSRCFLT3 | |
| SCHEMBL4767760 | 0.80 | CSF1R (0.61) | CSF1RNTRK1KITSRCFLT3 | |
| SCHEMBL4572826 | 0.77 | CSF1R (0.49) | CSF1RNTRK1KITSRCFLT3 | |
| SCHEMBL4768934 | 0.77 | CSF1R (0.45) | CSF1RNTRK1KITSRCFLT3 | |
| SCHEMBL4775794 | 0.76 | CSF1R (0.55) | CSF1RNTRK1KITSRCFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008055013-A2 | 5-OXO-5,8 - DIHYDRO - PYRIDO - PYRIMIDINES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-05-08 | — | — | WO | claimed |