Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 20/20 | 0.55 |
| ▸ | KIT | P10721 | 3/20 | 0.42 |
| ▸ | SRC | P12931 | 3/20 | 0.42 |
| ▸ | FLT3 | P36888 | 3/20 | 0.42 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.42 |
| ▸ | INSR | P06213 | 2/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4777730 | 0.91 | CSF1R (0.57) | CSF1RKITSRCFLT3NTRK1 | |
| SCHEMBL4775791 | 0.88 | CSF1R (0.39) | CSF1R | |
| SCHEMBL4775457 | 0.84 | CSF1R (0.57) | CSF1RKITSRCFLT3NTRK1 | |
| SCHEMBL4572926 | 0.81 | CSF1R (0.53) | CSF1RKITSRCFLT3NTRK1 | |
| SCHEMBL4775792 | 0.80 | SLC6A2 (0.38) | CSF1R | |
| SCHEMBL4777309 | 0.79 | CSF1R (0.57) | CSF1RKITSRCFLT3NTRK1 | |
| SCHEMBL4771530 | 0.79 | CSF1R (0.57) | CSF1RKITSRCFLT3NTRK1 | |
| SCHEMBL4768934 | 0.78 | CSF1R (0.45) | CSF1RKITSRCFLT3NTRK1 | |
| SCHEMBL3289970 | 0.77 | CSF1R (0.65) | CSF1RKITSRCFLT3NTRK1 | |
| SCHEMBL3527041 | 0.77 | CSF1R (0.79) | CSF1RKITSRCFLT3NTRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945637-A1 | 5-OXO-5,8-DIHYDRO-PYRIDO-PYRIMIDINES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA N.V. (BE) | 2008-07-23 | — | — | EP | disclosed |
| WO-2007033137-A1 | 5-OXO-5,8-DIHYDRO-PYRIDO-PYRIMIDINES AS INHIBITORS OF C-FMS KINASE | JANSSEN PHARMACEUTICA, N.V. (BE) | 2007-03-22 | — | — | WO | disclosed |