SCHEMBL4573142

SCHEMBL4573142

CCCOC(=O)C(=Cc1ccc(O)c(OC)c1)C(C)=O

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.71
TDP1 Q9NUW8 3/20 0.55
GAA P10253 2/20 0.55
GLO1 Q04760 4/20 0.54
ABL1 P00519 1/20 0.54
ALDH1A1 P00352 3/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
KDM4E B2RXH2 3/20 0.53
POLB P06746 2/20 0.53
IKBKB O14920 1/20 0.51
CHUK O15111 1/20 0.51
IKBKG Q9Y6K9 1/20 0.51
MAOB P27338 2/20 0.50
APP P05067 3/20 0.49
SNCA P37840 3/20 0.48
CYP2D6 P10635 3/20 0.48
CYP2C9 P11712 2/20 0.48
TSHR P16473 2/20 0.48
HSD17B10 Q99714 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4739625 0.92 MAPT (0.66) MAPTTDP1GAAGLO1ABL1
SCHEMBL2255275 0.90 MAPT (0.74) MAPTTDP1GAAGLO1ABL1
SCHEMBL2211638 0.90 MAPT (0.74) MAPTTDP1GAAGLO1ABL1
SCHEMBL2216850 0.87 MAPT (0.66) MAPTTDP1GAAGLO1ABL1
SCHEMBL5011134 0.86 ALOX5 (0.58) MAPTTDP1GAAGLO1MEN1
SCHEMBL2215798 0.84 MAPT (0.69) MAPTTDP1GAAGLO1ABL1
SCHEMBL7523992 0.84 MAPT (1.00) MAPTTDP1GAAGLO1ABL1
SCHEMBL934307 0.83 MAPT (0.70) MAPTTDP1GAAGLO1ABL1
SCHEMBL29799957 0.83 MAPT (0.70) MAPTTDP1GAAGLO1ABL1
SCHEMBL2268635 0.81 MAPT (0.58) MAPTTDP1GAAGLO1ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008083975-A1 LIGHT-STABILIZED COMPOSITION ISDIN S.A. (ES) 2008-07-17 WO claimed