Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | GLO1 | Q04760 | 2/20 | 0.46 |
| ▸ | ABL1 | P00519 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | IKBKB | O14920 | 1/20 | 0.43 |
| ▸ | CHUK | O15111 | 1/20 | 0.43 |
| ▸ | IKBKG | Q9Y6K9 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.41 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL490861 | 0.95 | MAPT (0.52) | MAPTTDP1LMNAALDH1A1MEN1 | |
| SCHEMBL23530142 | 0.89 | TDP1 (0.45) | MAPTTDP1LMNAALDH1A1GAA | |
| SCHEMBL2267509 | 0.89 | TDP1 (0.45) | MAPTTDP1LMNAALDH1A1GAA | |
| SCHEMBL8330361 | 0.86 | TDP1 (0.52) | MAPTTDP1LMNAALDH1A1MEN1 | |
| SCHEMBL20395702 | 0.85 | LMNA (0.48) | MAPTTDP1LMNAALDH1A1MEN1 | |
| SCHEMBL20395676 | 0.84 | LMNA (0.47) | MAPTTDP1LMNAALDH1A1MEN1 | |
| SCHEMBL8436026 | 0.84 | TDP1 (0.64) | MAPTTDP1LMNAALDH1A1MEN1 | |
| SCHEMBL8436027 | 0.84 | TDP1 (0.64) | MAPTTDP1LMNAALDH1A1MEN1 | |
| SCHEMBL30632224 | 0.84 | TDP1 (0.47) | MAPTTDP1LMNAALDH1A1CA2 | |
| SCHEMBL490643 | 0.84 | LMNA (0.53) | TDP1LMNAALDH1A1CA2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1635777-B1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GMBH (DE) | 2012-06-06 | — | — | EP | claimed |
| US-8003082-B2 | Photostable organic sunscreen composition | MERCK PATENT GMBH (DE) | 2011-08-23 | — | — | US | claimed |
| US-20100047185-A1 | ACTVIE SUBSTANCE COMBINATION | ISDIN S.A. (ES) | 2010-02-25 | — | — | US | claimed |
| WO-2008083975-A1 | LIGHT-STABILIZED COMPOSITION | ISDIN S.A. (ES) | 2008-07-17 | — | — | WO | claimed |
| WO-2008083974-A1 | ACTIVE SUBSTANCE COMBINATION | ISDIN S.A. (ES) | 2008-07-17 | — | — | WO | claimed |
| WO-2008067928-A1 | UV ABSORBING COMPOSITIONS CONTAINING A PYRROLYLTRIAZINE | ISDIN S.A. (ES) | 2008-06-12 | — | — | WO | claimed |
| US-20070059258-A1 | Photostable organic sunscreen composition | MERCK PATENT GMBH (DE) | 2007-03-15 | — | — | US | claimed |
| EP-1747773-A2 | Photostable organic sunscreen compositions with antioxidant properties | Merck Patent GmbH (DE) | 2007-01-31 | — | — | EP | claimed |
| US-7166273-B2 | Photo stable organic sunscreen compositions | EMD CHEMICALS, INC. (US) | 2007-01-23 | — | — | US | claimed |
| US-7150876-B2 | Methods for stabilizing ingredients within cosmetics, personal care and household products | MERCK PATENT GMBH (DE) | 2006-12-19 | — | — | US | claimed |
| EP-1635777-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GmbH (DE) | 2006-03-22 | — | — | EP | claimed |
| US-20050244349-A1 | Methods for stabilizing ingredients within cosmetics, personal care and household products | SUSONITY Commercial GmbH (DE) | 2005-11-03 | — | — | US | claimed |
| EP-1591099-A2 | Methods for stabilizing ingredients within cosmetics, personal care and household products | MERCK PATENT GmbH (DE) | 2005-11-02 | — | — | EP | claimed |
| US-6831191-B2 | Blocking ultraviolet radiation on skin | EM INDUSTRIES | 2004-12-14 | — | — | US | claimed |
| WO-2004105712-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GMBH (DE) | 2004-12-09 | — | — | WO | claimed |
| US-20040247536-A1 | Photo stable organic sunscreen compositions | EMD CHEMICALS, INC. | 2004-12-09 | — | — | US | claimed |
| EP-1406582-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GmbH (DE) | 2004-04-14 | — | — | EP | claimed |
| US-20030157035-A1 | PHOTO STABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | EM INDUSTRIES | 2003-08-21 | — | — | US | claimed |
| WO-2003007906-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GMBH (DE) | 2003-01-30 | — | — | WO | claimed |
| EP-1635777-B1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GMBH (DE) | 2012-06-06 | — | — | EP | disclosed |
| US-8003082-B2 | Photostable organic sunscreen composition | MERCK PATENT GMBH (DE) | 2011-08-23 | — | — | US | disclosed |
| US-20100047185-A1 | ACTVIE SUBSTANCE COMBINATION | ISDIN S.A. (ES) | 2010-02-25 | — | — | US | disclosed |
| EP-1952843-A1 | Photostable organic sunscreen compounds with antioxidant properties and compositions obtained therefrom | Merck Patent GmbH (DE) | 2008-08-06 | — | — | EP | disclosed |
| WO-2008083975-A1 | LIGHT-STABILIZED COMPOSITION | ISDIN S.A. (ES) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008083974-A1 | ACTIVE SUBSTANCE COMBINATION | ISDIN S.A. (ES) | 2008-07-17 | — | — | WO | disclosed |
| WO-2008067928-A1 | UV ABSORBING COMPOSITIONS CONTAINING A PYRROLYLTRIAZINE | ISDIN S.A. (ES) | 2008-06-12 | — | — | WO | disclosed |
| US-20070059258-A1 | Photostable organic sunscreen composition | MERCK PATENT GMBH (DE) | 2007-03-15 | — | — | US | disclosed |
| EP-1747773-A2 | Photostable organic sunscreen compositions with antioxidant properties | Merck Patent GmbH (DE) | 2007-01-31 | — | — | EP | disclosed |
| US-7166273-B2 | Photo stable organic sunscreen compositions | EMD CHEMICALS, INC. (US) | 2007-01-23 | — | — | US | disclosed |
| US-7150876-B2 | Methods for stabilizing ingredients within cosmetics, personal care and household products | MERCK PATENT GMBH (DE) | 2006-12-19 | — | — | US | disclosed |
| EP-1635777-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GmbH (DE) | 2006-03-22 | — | — | EP | disclosed |
| US-20050244349-A1 | Methods for stabilizing ingredients within cosmetics, personal care and household products | SUSONITY Commercial GmbH (DE) | 2005-11-03 | — | — | US | disclosed |
| EP-1591099-A2 | Methods for stabilizing ingredients within cosmetics, personal care and household products | MERCK PATENT GmbH (DE) | 2005-11-02 | — | — | EP | disclosed |
| US-6831191-B2 | Blocking ultraviolet radiation on skin | EM INDUSTRIES | 2004-12-14 | — | — | US | disclosed |
| WO-2004105712-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOSITION | MERCK PATENT GMBH (DE) | 2004-12-09 | — | — | WO | disclosed |
| US-20040247536-A1 | Photo stable organic sunscreen compositions | EMD CHEMICALS, INC. | 2004-12-09 | — | — | US | disclosed |
| EP-1406582-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GmbH (DE) | 2004-04-14 | — | — | EP | disclosed |
| US-20030157035-A1 | PHOTO STABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | EM INDUSTRIES | 2003-08-21 | — | — | US | disclosed |
| WO-2003007906-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GMBH (DE) | 2003-01-30 | — | — | WO | disclosed |
| WO-2003007906-A1 | PHOTOSTABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | MERCK PATENT GMBH (DE) | 2003-01-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050244349-A1 | Methods for stabilizing ingredients within cosmetics, personal care and household products | CUTA, TYR, LAGE3 | MAPT 328/4885TDP1 2596/4885LMNA 1379/4885 |
| US-20070059258-A1 | Photostable organic sunscreen composition | SUN2, ERCC1, PPOX | MAPT 105/4885TDP1 1702/4885LMNA 3000/4885 |
| US-20030157035-A1 | PHOTO STABLE ORGANIC SUNSCREEN COMPOUNDS WITH ANTIOXIDANT PROPERTIES AND COMPOSITIONS OBTAINED THEREFROM | ERCC1, ERCC4, OGG1 | MAPT 1564/4885TDP1 1533/4885LMNA 1536/4885 |
| US-20100047185-A1 | ACTVIE SUBSTANCE COMBINATION | UGT2B17, TACR2, UGT1A1 | MAPT 922/4885TDP1 3656/4885LMNA 1819/4885 |
| US-20040247536-A1 | Photo stable organic sunscreen compositions | SUN2, CCNB1, TYR | MAPT 272/4885TDP1 2418/4885LMNA 2596/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.