Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3987935 | 0.79 | MAPT (0.30) | — | |
| Acetonitrile SCHEMBL28876901 | 0.75 | NOTUM (0.31) | — | |
| SCHEMBL17464296 | 0.75 | TSHR (0.35) | — | |
| SCHEMBL8109165 | 0.75 | HDAC3 (0.38) | — | |
| SCHEMBL3865379 | 0.74 | ACHE (0.32) | — | |
| SCHEMBL15648152 | 0.73 | CYP11B1 (0.33) | CYP11B1CYP11B2 | |
| SCHEMBL31292657 | 0.72 | CYP11B1 (0.31) | CYP11B1CYP11B2 | |
| SCHEMBL21718898 | 0.71 | TSHR (0.32) | — | |
| SCHEMBL6965456 | 0.71 | ALDH1A1 (0.36) | — | |
| SCHEMBL1626451 | 0.71 | AR (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001127-A1 | CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |
| WO-2009001127-A1 | CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |